Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …

Retinoic acid (RA) modulates transcription of numerous target genes, thereby regulating a
myriad of biological processes. It is well established that RA functions by activating retinoic …

Retinoic acid (RA) modulates cell proliferation, differentiation, and apoptosis, and is used in
chemotherapy and chemoprevention in several human cancers. RA exerts its pleiotropic …

The unique properties of gold nanoparticles (AuNPs) have attracted much interest for a
range of applications, including biomedical applications in the cosmetic industry. The current …

Retinoic acid (RA) is known to regulate cell growth and differentiation. In HL-60 human
myeloblastic leukemia cells, it causes mitogen-activated protein kinase (MAPK) signaling …

All-trans–retinoic acid (RA), a potent inducer of cellular differentiation, functions as a ligand
for retinoic acid receptors (RARα, β, and γ). RARs are activated by ligand binding, which …

The role of NF-kB in regulating G1 arrest in maturation induced by the histone deacetylase
inhibitor sodium butyrate (NaB) was examined in human myelomonocytic leukemia cells …

The network and balance of cytokines is of major importance in maintaining proper
homeostasis of hematopoiesis. Abnormalities in this network may result in a variety of blood …

All-trans retinoic acid (RA) and interferons (IFNs) have efficacy in treating certain leukemias
and lymphomas, respectively, motivating interest in their mechanism of action to improve …

Retinoic acid‐induced expression of the CD38 ectoenzyme receptor in HL‐60 human
myeloblastic leukemia cells is regulated by RARα and RXR, and enhanced or prevented cell …