Fibrillar collagen: a review of the mechanical modeling of strain-mediated enzymatic turnover

H Topol, H Demirkoparan… - Applied …, 2021 - asmedigitalcollection.asme.org
Collagen is the most abundant protein in mammals, often serving as the main load bearing
constituent in soft tissues. Collagen undergoes continuous remodeling processes in which …

Abdominal aortic aneurysm pathomechanics: current understanding and future directions

EMC Kemmerling, RA Peattie - … , cellular, and tissue engineering of the …, 2018 - Springer
Abdominal aortic aneurysms (AAAs) are permanent, local expansions of the abdominal
segment of the aorta that can potentially be fatal if progressing to rupture. AAAs are rarely …

Patient-specific predictions of aneurysm growth and remodeling in the ascending thoracic aorta using the homogenized constrained mixture model

SJ Mousavi, S Farzaneh, S Avril - Biomechanics and modeling in …, 2019 - Springer
In its permanent quest of mechanobiological homeostasis, our vasculature significantly
adapts across multiple length and timescales in various physiological and pathological …

A quarter of a century biomechanical rupture risk assessment of abdominal aortic aneurysms. Achievements, clinical relevance, and ongoing developments

TC Gasser, C Miller, S Polzer… - International journal for …, 2023 - Wiley Online Library
Abdominal aortic aneurysm (AAA) disease, the local enlargement of the infrarenal aorta, is a
serious condition that causes many deaths, especially in men exceeding 65 years of age …

An asymptotic homogenization approach to the microstructural evolution of heterogeneous media

A Ramírez-Torres, S Di Stefano, A Grillo… - International Journal of …, 2018 - Elsevier
In the present work, we apply the asymptotic homogenization technique to the equations
describing the dynamics of a heterogeneous material with evolving micro-structure, thereby …

A finite element implementation of a growth and remodeling model for soft biological tissues: Verification and application to abdominal aortic aneurysms

N Horvat, L Virag, GA Holzapfel, J Sorić… - Computer methods in …, 2019 - Elsevier
The general framework for growth and remodeling (G&R) of soft biological tissues shows a
great potential for expanding our current understanding of biochemical and biomechanical …

Anisotropic stiffness and tensional homeostasis induce a natural anisotropy of volumetric growth and remodeling in soft biological tissues

FA Braeu, RC Aydin, CJ Cyron - Biomechanics and modeling in …, 2019 - Springer
Growth in soft biological tissues in general results in anisotropic changes of the tissue
geometry. It remains a key challenge in biomechanics to understand, quantify, and predict …

Computational study of growth and remodeling in ascending thoracic aortic aneurysms considering variations of smooth muscle cell basal tone

A Ghavamian, SJ Mousavi, S Avril - Frontiers in Bioengineering and …, 2020 - frontiersin.org
In this paper, we investigate the progression of Ascending Thoracic Aortic Aneurysms
(ATAA) using a computational model of Growth and Remodeling (G&R) taking into account …

About prestretch in homogenized constrained mixture models simulating growth and remodeling in patient-specific aortic geometries

JD Laubrie, SJ Mousavi, S Avril - Biomechanics and modeling in …, 2022 - Springer
Evolution of mechanical and structural properties in the Ascending Thoracic Aorta (ATA) is
the results of complex mechanobiological processes. In this work, we address some …

Fast, rate-independent, finite element implementation of a 3D constrained mixture model of soft tissue growth and remodeling

M Latorre, JD Humphrey - Computer methods in applied mechanics and …, 2020 - Elsevier
Constrained mixture models of soft tissue growth and remodeling can simulate many
evolving conditions in health as well as in disease and its treatment, but they can be …