Patient-specific modeling of dyssynchronous heart failure: a case study

J Aguado-Sierra, A Krishnamurthy, C Villongco… - Progress in biophysics …, 2011 - Elsevier
The development and clinical use of patient-specific models of the heart is now a feasible
goal. Models have the potential to aid in diagnosis and support decision-making in clinical …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

[HTML][HTML] Images as drivers of progress in cardiac computational modelling

P Lamata, R Casero, V Carapella, SA Niederer… - Progress in biophysics …, 2014 - Elsevier
Computational models have become a fundamental tool in cardiac research. Models are
evolving to cover multiple scales and physical mechanisms. They are moving towards …

Myosin light chain phosphorylation is critical for adaptation to cardiac stress

SA Warren, LE Briggs, H Zeng, J Chuang, EI Chang… - Circulation, 2012 - Am Heart Assoc
Background—Cardiac hypertrophy is a common response to circulatory or neurohumoral
stressors as a mechanism to augment contractility. When the heart is under sustained stress …

Orthotropic active strain models for the numerical simulation of cardiac biomechanics

S Rossi, R Ruiz‐Baier, LF Pavarino… - … journal for numerical …, 2012 - Wiley Online Library
SUMMARY A model for the active deformation of cardiac tissue considering orthotropic
constitutive laws is introduced and studied. In particular, the passive mechanical properties …

Improved identifiability of myocardial material parameters by an energy-based cost function

A Nasopoulou, A Shetty, J Lee, D Nordsletten… - … and modeling in …, 2017 - Springer
Myocardial stiffness is a valuable clinical biomarker for the monitoring and stratification of
heart failure (HF). Cardiac finite element models provide a biomechanical framework for the …

An inverse finite element method for determining the tissue compressibility of human left ventricular wall during the cardiac cycle

AI Hassaballah, MA Hassan, AN Mardi, M Hamdi - PloS one, 2013 - journals.plos.org
The determination of the myocardium's tissue properties is important in constructing
functional finite element (FE) models of the human heart. To obtain accurate properties …

Modeling and simulation of fish swimming with active muscles

M Curatolo, L Teresi - Journal of theoretical biology, 2016 - Elsevier
Our goal is to reproduce the key features of carangiform swimming by modeling muscle
functioning using the notion of active distortions, thus emphasizing the kinematical role of …

The multiplicative decomposition of the deformation gradient in the multiphysics modeling of ionic polymers

S Galante, A Lucantonio, P Nardinocchi - International Journal of Non …, 2013 - Elsevier
A thermodynamically consistent modeling of the non-linear multiphysics behavior of ionic
polymers is presented and discussed. A key ingredient of the model is the treatment of the …

4D-analysis of left ventricular heart cycle using procrustes motion analysis

P Piras, A Evangelista, S Gabriele, P Nardinocchi… - PloS one, 2014 - journals.plos.org
The aim of this study is to investigate human left ventricular heart morphological changes in
time among 17 healthy subjects. Preliminarily, 2 patients with volumetric overload due to …