Integrated MRI-guided radiotherapy—opportunities and challenges

PJ Keall, C Brighi, C Glide-Hurst, G Liney… - Nature Reviews …, 2022 - nature.com
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

WA Hall, E Paulson, XA Li, B Erickson… - CA: a cancer journal …, 2022 - Wiley Online Library
Radiation therapy (RT) continues to play an important role in the treatment of cancer.
Adaptive RT (ART) is a novel method through which RT treatments are evolving. With the …

Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

M Reyngold, EM O'Reilly, AM Varghese… - JAMA …, 2021 - jamanetwork.com
Importance Surgical resection has been considered the only curative option for patients with
pancreatic cancer. Nonoperative local treatment options that can provide a similar benefit …

[HTML][HTML] MR-guidance in clinical reality: current treatment challenges and future perspectives

S Corradini, F Alongi, N Andratschke, C Belka… - Radiation …, 2019 - Springer
Abstract Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new
era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct …

[HTML][HTML] Ablative 5-fraction stereotactic magnetic resonance–guided radiation therapy with on-table adaptive replanning and elective nodal irradiation for inoperable …

MD Chuong, J Bryant, KE Mittauer, M Hall… - Practical radiation …, 2021 - Elsevier
Purpose Radiation therapy dose escalation using stereotactic body radiation therapy may
significantly improve both local control (LC) and overall survival (OS) for patients with …

[HTML][HTML] Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy

W Xia, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …

[HTML][HTML] The transformation of radiation oncology using real-time magnetic resonance guidance: A review

WA Hall, ES Paulson, UA van der Heide… - European Journal of …, 2019 - Elsevier
Radiation therapy (RT) is an essential component of effective cancer care and is used
across nearly all cancer types. The delivery of RT is becoming more precise through rapid …

[HTML][HTML] Ablative five-fraction stereotactic body radiation therapy for inoperable pancreatic cancer using online MR-guided adaptation

C Hassanzadeh, S Rudra, A Bommireddy… - Advances in radiation …, 2021 - Elsevier
Purpose Patients with inoperable pancreatic adenocarcinoma have limited options, with
traditional chemoradiation providing modest clinical benefit and an otherwise poor …

MRI-guided adaptive radiotherapy for liver tumours: visualising the future

JS Witt, SA Rosenberg, MF Bassetti - The Lancet Oncology, 2020 - thelancet.com
MRI-guided radiotherapy is a novel and rapidly evolving technology that might enhance the
risk–benefit ratio. Through direct visualisation of the tumour and the nearby healthy tissues …

Image guidance in radiation therapy for better cure of cancer

V Grégoire, M Guckenberger… - Molecular …, 2020 - Wiley Online Library
The key goal and main challenge of radiation therapy is the elimination of tumors without
any concurring damages of the surrounding healthy tissues and organs. Radiation doses …