Natural hydrogel-based bio-inks for 3D bioprinting in tissue engineering: a review

A Fatimi, OV Okoro, D Podstawczyk, J Siminska-Stanny… - Gels, 2022 - mdpi.com
Three-dimensional (3D) printing is well acknowledged to constitute an important technology
in tissue engineering, largely due to the increasing global demand for organ replacement …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts

M Rafat, M Jabbarvand, N Sharma, M Xeroudaki… - Nature …, 2023 - nature.com
Visual impairment from corneal stromal disease affects millions worldwide. We describe a
cell-free engineered corneal tissue, bioengineered porcine construct, double crosslinked …

[HTML][HTML] Dual-crosslinked regenerative hydrogel for sutureless long-term repair of corneal defect

X Shen, S Li, X Zhao, J Han, J Chen, Z Rao, K Zhang… - Bioactive Materials, 2023 - Elsevier
Corneal transplantation is the most effective clinical treatment for corneal defects, but it
requires precise size of donor corneas, surgical sutures, and overcoming other technical …

Mimicking the hierarchical organization of natural collagen: toward the development of ideal scaffolding material for tissue regeneration

L Salvatore, N Gallo, ML Natali, A Terzi… - … in Bioengineering and …, 2021 - frontiersin.org
Biological materials found in living organisms, many of which are proteins, feature a
complex hierarchical organization. Type I collagen, a fibrous structural protein ubiquitous in …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

[HTML][HTML] Tissue adhesive hyaluronic acid hydrogels for sutureless stem cell delivery and regeneration of corneal epithelium and stroma

L Koivusalo, M Kauppila, S Samanta, VS Parihar… - Biomaterials, 2019 - Elsevier
Regeneration of a severely damaged cornea necessitates the delivery of both epithelium-
renewing limbal epithelial stem cells (LESCs) and stroma-repairing cells, such as human …

Preparation and in vitro characterization of cross-linked collagen–gelatin hydrogel using EDC/NHS for corneal tissue engineering applications

H Goodarzi, K Jadidi, S Pourmotabed, E Sharifi… - International journal of …, 2019 - Elsevier
Corneal disease is considered as the second leading cause of vision loss and keratoplasty
is known as an effective treatment for it. However, the tissue engineered corneal substitutes …

[HTML][HTML] Functional acellular matrix for tissue repair

B Wang, T Qinglai, Q Yang, M Li, S Zeng, X Yang… - Materials Today Bio, 2023 - Elsevier
In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Corneal repair and regeneration: current concepts and future directions

M Mobaraki, R Abbasi, S Omidian Vandchali… - … in Bioengineering and …, 2019 - frontiersin.org
The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …