Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases

M Candelli, L Franza, G Pignataro, V Ojetti… - International journal of …, 2021 - mdpi.com
Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative
bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context …

Mechanotransduction in skin inflammation

MS Shutova, WH Boehncke - Cells, 2022 - mdpi.com
In the process of mechanotransduction, the cells in the body perceive and interpret
mechanical stimuli to maintain tissue homeostasis and respond to the environmental …

Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue

H Wang, CN Alarcón, B Liu, F Watson… - Nature biomedical …, 2022 - nature.com
Targeting the delivery of therapeutics specifically to diseased tissue enhances their efficacy
and decreases their side effects. Here we show that mesenchymal stromal cells with their …

The biology of vascular calcification

D Quaglino, F Boraldi, FD Lofaro - … review of cell and molecular biology, 2020 - Elsevier
Vascular calcification (VC), characterized by different mineral deposits (ie, carbonate apatite,
whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a …

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

A Parkin, J Man, P Timpson, M Pajic - The FEBS journal, 2019 - Wiley Online Library
Pancreatic cancer, a disease with extremely poor prognosis, has been notoriously resistant
to virtually all forms of treatment. The dynamic crosstalk that occurs between tumour cells …

Early events in Japanese encephalitis virus infection: Viral entry

SI Yun, YM Lee - Pathogens, 2018 - mdpi.com
Japanese encephalitis virus (JEV), a mosquito-borne zoonotic flavivirus, is an enveloped
positive-strand RNA virus that can cause a spectrum of clinical manifestations, ranging from …

Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer

Y Iwatate, H Yokota, I Hoshino, F Ishige, N Kuwayama… - PLoS …, 2022 - journals.plos.org
Transcriptomic analysis of cancer samples helps identify the mechanism and molecular
markers of cancer. However, transcriptomic analyses of pancreatic cancer from the …

Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses

GR You, AJ Cheng, LY Lee, YC Huang, H Liu, YJ Chen… - BMC cancer, 2019 - Springer
Background Radiotherapy is an indispensable treatment modality in head and neck cancer
(HNC), while radioresistance is the major cause of treatment failure. The aim of this study is …

[HTML][HTML] Virus-host Interactions in Early Japanese Encephalitis Virus Infection

Y Zhu, Z He, Z Qi - Virus Research, 2023 - Elsevier
Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic virus that can cause severe
viral encephalitis. Initial interactions between JEV and host cells are required for productive …

Integrins: moonlighting proteins in invadosome formation

R Peláez, A Pariente, Á Pérez-Sala, IM Larrayoz - Cancers, 2019 - mdpi.com
Invadopodia are actin-rich protrusions developed by transformed cells in 2D/3D
environments that are implicated in extracellular matrix (ECM) remodeling and degradation …