Lessons for understanding central nervous system HIV reservoirs from the last gift program

PK Riggs, A Chaillon, G Jiang, SL Letendre… - Current HIV/AIDS …, 2022 - Springer
Abstract Purpose of Review Deep tissue HIV reservoirs, especially within the central
nervous system (CNS), are understudied due to the challenges of sampling brain, spinal …

The relationship between HIV‐1 neuroinflammation, neurocognitive impairment and encephalitis pathology: A systematic review of studies investigating post‐mortem …

ME Williams, PJW Naudé - Reviews in Medical Virology, 2024 - Wiley Online Library
The activities of HIV‐1 in the central nervous system (CNS) are responsible for a
dysregulated neuroinflammatory response and the subsequent development of HIV …

[HTML][HTML] Plasma biomarkers of vascular dysfunction uniquely relate to a vascular-risk profile of neurocognitive deficits in virally-suppressed adults with HIV

R Saloner, N Sun-Suslow, EE Morgan, J Lobo… - Brain, Behavior, & …, 2022 - Elsevier
Objective Chronic inflammation and vascular dysfunction (eg, chronic endothelial activation)
are related yet dissociable mechanisms of HIV-associated neurocognitive impairment (NCI) …

Cohort profile: PRESTIGIO, an Italian prospective registry-based cohort of people with HIV-1 resistant to reverse transcriptase, protease and integrase inhibitors

T Clemente, L Galli, R Lolatto, R Gagliardini, F Lagi… - BMJ open, 2024 - bmjopen.bmj.com
Purpose The PRESTIGIO Registry was established in 2017 to collect clinical, virological and
immunological monitoring data from people living with HIV (PLWH) with documented four …

[HTML][HTML] Pillars of long-term antiretroviral therapy success

L Taramasso, M Andreoni, A Antinori, A Bandera… - Pharmacological …, 2023 - Elsevier
Background Meeting the challenge of antiretroviral therapy (ART) whose efficacy can last a
lifetime requires continuous updating of the virological, pharmacological, and quality of life …

Peripheral immune dysregulation in the ART era of HIV-associated neurocognitive impairments: A systematic review

ME Williams, JC Ipser, DJ Stein, JA Joska… - …, 2020 - Elsevier
Human immunodeficiency virus-associated neurocognitive impairment (HANI) remains
problematic despite the effective use of antiretroviral therapy (ART) and viral suppression. A …

Demographically-adjusted norms for the Grooved Pegboard and Finger Tapping tests in Spanish-speaking adults: Results from the Neuropsychological Norms for the …

A Heaton, A Gooding, M Cherner… - The Clinical …, 2021 - Taylor & Francis
Objective We developed demographically-corrected norms for Spanish-speakers from the
US-Mexico border regions of California and Arizona on two tests of motor skills-the Grooved …

Chronically elevated depressive symptoms interact with acute increases in inflammation to predict worse neurocognition among people with HIV

R Saloner, EW Paolillo, RK Heaton, DJ Grelotti… - Journal of …, 2021 - Springer
We examined the joint effects of depressive symptoms (Beck Depression Inventory-II (BDI-
II)) and systemic inflammation (plasma C-reactive protein (CRP)) on longitudinal profiles of …

Cognition, structural brain changes, and systemic inflammation in adolescents living with HIV on antiretroviral therapy

J Hoare, L Myer, S Heany, JP Fouche… - JAIDS Journal of …, 2020 - journals.lww.com
Objective: To investigate the association between neurocognitive impairment,
neuroimaging, and systemic inflammation in perinatally infected adolescents living with HIV …

Characteristics of motor dysfunction in longstanding human immunodeficiency virus

J Robinson-Papp, G Gensler, A Navis… - Clinical Infectious …, 2020 - academic.oup.com
Background Cognitive dysfunction in human immunodeficiency virus (HIV) has decreased,
but milder forms of HIV-associated neurocognitive disorders (HAND) persist along with …