Donor age was identified recently as a major factor that determines long-term outcome after
transplantation, but the mechanism that is responsible for increased graft loss of old donor …

The shortage of cadaveric donor kidneys for transplantation has forced a re‐evaluation of
the limits on donor age acceptability. However, as more kidneys from older donors have …

Background. The results of the transplantation of marginal donor kidneys remain
controversial. This study aimed to investigate the impact of donor risk factors as predictors of …

The predictive value of pre-implantation biopsies versus clinical scores has not been studied
extensively in marginal donors. Pre-implantation biopsies were performed in 313 kidneys …

Renal transplantation is an accepted and successful treatment modality in elderly patients
with end-stage renal disease. In comparison with maintenance dialysis, transplantation has …

Background. The quality of a damaged kidney, the complexity of the surgery, and the events
in the first weeks after transplantation, such as delayed graft function (DGF) and acute …

The organ shortage has led to extend the procurement to kidneys from 'marginal'donors. As
a result, an increasing number of kidneys are discarded, but an extended analysis of the …

WT1 and Pax2 are transcription factors involved in kidney development and phenotypic
regulation of glomerular epithelial cells. In primary focal segmental glomerulosclerosis …

Background Despite the increasing use of older living donors in kidney transplantation,
intermediate-term donor and recipient outcomes are poorly characterized. Methods We …

PURPOSE: Marginal cadaveric renal transplant donors represent a potential source for
expansion of the donor pool but these kidneys have generally demonstrated significantly …