Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila due to rapid developments in molecular genetics approaches that overcome the difficulties …
Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological and pathological processes. A longstanding yet largely unmet goal is to measure DA …
Mapping neural circuits across defined synapses is essential for understanding brain function. Here we describe trans-Tango, a technique for anterograde transsynaptic circuit …
Various insect species serve as valuable model systems for investigating the cellular and molecular mechanisms by which a brain controls sophisticated behaviors. In particular, the …
The definition of neuronal type and how it relates to the transcriptome are open questions. Drosophila olfactory projection neurons (PNs) are among the best-characterized neuronal …
We describe a new repressible binary expression system based on the regulatory genes from the Neurospora qa gene cluster. This" Q system" offers attractive features for transgene …
Y Yamaguchi, M Miura - Developmental cell, 2015 - cell.com
Programmed cell death (PCD) is an evolutionarily conserved contributor to nervous system development. In the vertebrate peripheral nervous system, PCD is the basis of the …
D Yamamoto, M Koganezawa - Nature Reviews Neuroscience, 2013 - nature.com
In Drosophila melanogaster, the causal links among a complex behaviour, single neurons and single genes can be demonstrated through experimental manipulations. A key player in …
Research in the fruit fly Drosophila melanogaster has led to insights in neural development, axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …