Mechanisms of red blood cell transfusion‐related immunomodulation

KE Remy, MW Hall, J Cholette, NP Juffermans… - …, 2018 - Wiley Online Library
Red blood cell (RBC) transfusion is common in critically ill, postsurgical, and posttrauma
patients in whom both systemic inflammation and immune suppression are associated with …

Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention

EC Vamvakas, MA Blajchman - Blood, The Journal of the …, 2009 - ashpublications.org
As the risks of allogeneic blood transfusion (ABT)–transmitted viruses were reduced to
exceedingly low levels in the US, transfusion-related acute lung injury (TRALI), hemolytic …

Effects of red-cell storage duration on patients undergoing cardiac surgery

ME Steiner, PM Ness, SF Assmann… - … England Journal of …, 2015 - Mass Medical Soc
Background Some observational studies have reported that transfusion of red-cell units that
have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse …

Patient blood management in Europe

A Shander, H Van Aken, MJ Colomina… - British journal of …, 2012 - academic.oup.com
Preoperative anaemia is common in patients undergoing orthopaedic and other major
surgery. Anaemia is associated with increased risks of postoperative mortality and morbidity …

Transfusion of older stored blood and risk of death: a meta‐analysis

D Wang, J Sun, SB Solomon, HG Klein… - Transfusion, 2012 - Wiley Online Library
BACKGROUND: Blood for transfusion is stored for up to 42 days. Older blood develops
lesions and accumulates potentially injurious substances. Some studies report increasing …

Association of perioperative red blood cell transfusions with venous thromboembolism in a North American registry

R Goel, EU Patel, MM Cushing, SM Frank… - JAMA …, 2018 - jamanetwork.com
Importance Increasing evidence supports the role of red blood cells (RBCs) in physiological
hemostasis and pathologic thrombosis. Red blood cells are commonly transfused in the …

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

A Danesh, HC Inglis, RP Jackman, S Wu… - Blood, The Journal …, 2014 - ashpublications.org
Extracellular vesicles (EVs) are small, double membrane vesicles derived from leukocytes,
platelets, and cells of other tissues under physiological or pathological conditions …

Red cell changes during storage

JR Hess - Transfusion and Apheresis Science, 2010 - Elsevier
Red blood cells can be stored in liquid suspension in approved additive solutions for
periods up to 6weeks with 0.4% hemolysis, 84% 24-h in vivo recovery, and normal …

Resuscitation and transfusion principles for traumatic hemorrhagic shock

PC Spinella, JB Holcomb - Blood reviews, 2009 - Elsevier
The transfusion approach to massive hemorrhage has continually evolved since it began in
the early 1900s. It started with fresh whole blood and currently consists of virtually exclusive …

[HTML][HTML] Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from metabolism to proteomics

A D'Alessandro, GM D'Amici, S Vaglio, L Zolla - Haematologica, 2012 - ncbi.nlm.nih.gov
Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from
metabolism to proteomics - PMC Back to Top Skip to main content NIH NLM Logo Access keys …