Central nervous system (CNS) maintains a high level of metabolism, which leads to the
generation of large amounts of free radicals, and it is also one of the most vulnerable organs …

Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …

Mesenchymal stem cell-derived exosomes (MSC-Exo) have robust anti-inflammatory effects
in the treatment of neurological diseases such as epilepsy, stroke, or traumatic brain injury …

Oxidative stress is a key cause of ischemic stroke and an initiator of neuronal dysfunction
and death, mainly through the overproduction of peroxides and the depletion of antioxidants …

Reactive oxygen species (ROS) are a family of molecules that are continuously generated,
transformed and consumed in all living organisms as a consequence of aerobic life. The …

Abstract Significance: The thioredoxin (Trx) and glutathione (GSH) systems play important
roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress …

Cellular homeostasis plays a critical role in how an organism will develop and age.
Disruption of this fragile equilibrium is often associated with health degradation and …

Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age
and has become increasingly more common with advances in age. The number of …

Over the past five decades, thanatology has come to include the study of how individual
cells in our bodies die appropriately and inappropriately in response to physiological and …