Large-scale functional connectivity networks in the rodent brain

A Gozzi, AJ Schwarz - Neuroimage, 2016 - Elsevier
Abstract Resting-state functional Magnetic Resonance Imaging (rsfMRI) of the human brain
has revealed multiple large-scale neural networks within a hierarchical and complex …

The BTBR mouse model of idiopathic autism–current view on mechanisms

KZ Meyza, DC Blanchard - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental
disorder, with current estimates of more than 1% of affected children across nations. The …

mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity

M Pagani, N Barsotti, A Bertero, S Trakoshis… - Nature …, 2021 - nature.com
Postmortem studies have revealed increased density of excitatory synapses in the brains of
individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTOR …

Unique spatiotemporal fMRI dynamics in the awake mouse brain

D Gutierrez-Barragan, NA Singh, FG Alvino, L Coletta… - Current biology, 2022 - cell.com
Human imaging studies have shown that spontaneous brain activity exhibits stereotypic
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …

Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex

F Rocchi, C Canella, S Noei… - Nature …, 2022 - nature.com
While shaped and constrained by axonal connections, fMRI-based functional connectivity
reorganizes in response to varying interareal input or pathological perturbations. However …

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

J Grandjean, C Canella, C Anckaerts, G Ayrancı… - Neuroimage, 2020 - Elsevier
Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer
the possibility to non-invasively probe whole-brain network dynamics and to investigate the …

Infraslow state fluctuations govern spontaneous fMRI network dynamics

D Gutierrez-Barragan, MA Basson, S Panzeri, A Gozzi - Current Biology, 2019 - cell.com
Spontaneous brain activity as assessed with resting-state fMRI exhibits rich spatiotemporal
structure. However, the principles by which brain-wide patterns of spontaneous fMRI activity …

Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes

V Zerbi, M Pagani, M Markicevic, M Matteoli… - Molecular …, 2021 - nature.com
Abstract Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly
heterogeneous abnormalities in functional brain connectivity. However, the origin and …

Functional connectivity hubs of the mouse brain

A Liska, A Galbusera, AJ Schwarz, A Gozzi - Neuroimage, 2015 - Elsevier
Recent advances in functional connectivity methods have made it possible to identify brain
hubs—a set of highly connected regions serving as integrators of distributed neuronal …

Autism-associated 16p11. 2 microdeletion impairs prefrontal functional connectivity in mouse and human

A Bertero, A Liska, M Pagani, R Parolisi, ME Masferrer… - Brain, 2018 - academic.oup.com
Human genetic studies are rapidly identifying variants that increase risk for
neurodevelopmental disorders. However, it remains unclear how specific mutations impact …