TGF-β Regulation of T Cells
WJ Chen - Annual review of immunology, 2023 - annualreviews.org
Transforming growth factor β (TGF-β) is a key cytokine regulating the development,
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
The role of N6-methyladenosine (m6A) modification in the regulation of circRNAs
L Zhang, C Hou, C Chen, Y Guo, W Yuan, D Yin, J Liu… - Molecular cancer, 2020 - Springer
Abstract N 6-methyladenosine (m 6 A), the most abundant modification in eukaryotic cells,
regulates RNA transcription, processing, splicing, degradation, and translation. Circular …
regulates RNA transcription, processing, splicing, degradation, and translation. Circular …
m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways
Abstract N 6-methyladenosine (m6A) is the most common and abundant messenger RNA
modification, modulated by 'writers','erasers' and 'readers' of this mark,. In vitro data have …
modification, modulated by 'writers','erasers' and 'readers' of this mark,. In vitro data have …
T memory stem cells in health and disease
T memory stem (TSCM) cells are a rare subset of memory lymphocytes endowed with the
stem cell–like ability to self-renew and the multipotent capacity to reconstitute the entire …
stem cell–like ability to self-renew and the multipotent capacity to reconstitute the entire …
The genetics and molecular biology of T-ALL
T Girardi, C Vicente, J Cools… - Blood, The Journal of …, 2017 - ashpublications.org
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy caused by the
accumulation of genomic lesions that affect the development of T cells. For many years, it …
accumulation of genomic lesions that affect the development of T cells. For many years, it …
Developmental and functional control of natural killer cells by cytokines
Y Wu, Z Tian, H Wei - Frontiers in immunology, 2017 - frontiersin.org
Natural killer (NK) cells are effective in combating infections and tumors and as such are
tempting for adoptive transfer therapy. However, they are not homogeneous but can be …
tempting for adoptive transfer therapy. However, they are not homogeneous but can be …
The full spectrum of human naive T cells
T van den Broek, JAM Borghans… - Nature Reviews …, 2018 - nature.com
Naive T cells have long been regarded as a developmentally synchronized and fairly
homogeneous and quiescent cell population, the size of which depends on age, thymic …
homogeneous and quiescent cell population, the size of which depends on age, thymic …
Mechanisms of regulation of the chemokine-receptor network
The interactions of chemokines with their G protein-coupled receptors promote the migration
of leukocytes during normal immune function and as a key aspect of the inflammatory …
of leukocytes during normal immune function and as a key aspect of the inflammatory …
Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets
A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of
pathogens, and TCR repertoire size is believed to decline with age. However, the precise …
pathogens, and TCR repertoire size is believed to decline with age. However, the precise …
From vaccines to memory and back
Vaccines work by eliciting an immune response and consequent immunological memory
that mediates protection from infection or disease. Recently, new methods have been …
that mediates protection from infection or disease. Recently, new methods have been …