Umbilical cord Wharton's jelly‐derived mesenchymal stem cells (WJ‐MSCs) have recently
gained considerable attention in the field of regenerative medicine. Their high proliferation …

Accumulating evidence indicates that most primary Wharton's jelly mesenchymal stem cells
(WJ-MSCs) therapeutic potential is due to their paracrine activity, ie, their ability to modulate …

Background Kidney insults due to various pathogenic factors, such as trauma, infection, and
inflammation, can cause tubular epithelial cell injury and death, leading to acute kidney …

In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to
their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from …

Background Renal tubular epithelial–myofibroblast transdifferentiation (EMT) plays a key
role in the regulation of renal fibrosis. Exosomes derived from human umbilical cord …

Epithelial–mesenchymal transition (EMT) is an important biological process contributing to
kidney fibrosis and chronic kidney disease. This process is characterized by decreased …

Tissue loss and end-stage organ failure are serious health problems across the world.
Natural and synthetic polymer scaffold material based artificial organs play an important role …

Kidney regeneration is hindered by the limited pool of intrinsic reparative cells. Advanced
therapies targeting renal regeneration have the potential to alleviate the clinical and …

The extracellular matrix (ECM), a complex set of fibrillar proteins and proteoglycans,
supports the renal parenchyma and provides biomechanical and biochemical cues critical …

Fibrosis is a pathological process, that could result in permanent scarring and impairment of
the physiological function of the affected organ; this condition which is categorized under the …