CD4/CD8 ratio during human immunodeficiency virus treatment: time for routine monitoring?

R Ron, E Moreno, J Martínez-Sanz… - Clinical Infectious …, 2023 - academic.oup.com
In the last decade, studies in persons with HIV (PWH) on antiretroviral therapy (ART) have
shed light on the significance of persistently high CD8 counts and low CD4/CD8 ratios. A …

Definition of immunological nonresponse to antiretroviral therapy: a systematic review

R Rb-Silva, A Goios, C Kelly, P Teixeira… - JAIDS Journal of …, 2019 - journals.lww.com
Background: Terms and criteria to classify people living with HIV on antiretroviral therapy
who fail to achieve satisfactory CD4+ T-cell counts are heterogeneous, and need revision …

[HTML][HTML] Changes in T-cell subsets and clonal repertoire during chemoimmunotherapy with pembrolizumab and paclitaxel or capecitabine for metastatic triple-negative …

B Chun, J Pucilowska, SC Chang, I Kim… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Chemoimmunotherapy is a standard treatment for triple-negative breast cancer
(TNBC), however, the impacts of different chemotherapies on T-cell populations, which …

Determinants of restoration of CD4 and CD8 cell counts and their ratio in HIV-1–positive individuals with sustained virological suppression on antiretroviral therapy

L Gras, M May, LP Ryder, A Trickey… - JAIDS Journal of …, 2019 - journals.lww.com
Background: An increasing number of HIV-positive individuals now start antiretroviral
therapy (ART) with high CD4 cell counts. We investigated whether this makes restoration of …

[HTML][HTML] 德宏傣族景颇族自治州成年人HIV/AIDS抗病毒治疗后CD4+T淋巴细胞免疫重建及影响因素分析

俞海亮, 杨跃诚, 赵燕, 曹东冬, 金聪, 叶润华… - 中华流行病学 …, 2021 - html.rhhz.net
目的分析德宏傣族景颇族自治州(德宏州) 成年人HIV/AIDS 开始抗病毒治疗(ART) 后CD4+ T
淋巴细胞(CD4) 纵向变化特征及其影响因素. 方法对德宏州2007-2016 年开始ART …

High‐intensity focused ultrasound ablation combined with transcatheter arterial chemoembolization improves long‐term efficacy and prognosis of primary liver cancer

M Sun, P Shang, J Bai, S Li, M Li - Journal of Clinical …, 2021 - Wiley Online Library
Background To investigate the clinical efficacy of high‐intensity focused ultrasound (HIFU)
combined with transcatheter arterial chemoembolization (TACE) in the treatment of primary …

Immune recovery in HIV-1 infected patients with sustained viral suppression under long-term antiretroviral therapy in Ethiopia

D Wolday, D Legesse, Y Kebede, DS Siraj… - PLoS …, 2020 - journals.plos.org
Background There is very little data on long-term immune recovery responses in patients on
suppressive antiretroviral therapy (ART) in the setting of sub-Saharan Africa (SSA). Thus, we …

A novel prediction model to evaluate the probability of CD4+/CD8+ cell ratio restoration in HIV-infected individuals

B Li, L Zhang, Y Liu, J Xiao, C Li, L Fan, Y Duan, J Xiao… - AIDS, 2022 - journals.lww.com
Background: Our study aimed to develop a clinical prediction model to evaluate the
possibility of CD4+/CD8+ ratio restoration in HIV-positive individuals. Methods: About 1980 …

Epidemiological trends of severely immunosuppressed people living with HIV at time of starting antiretroviral treatment in China during 2005–2018

Y Hou, J Liu, Y Zhao, Y Wu, Y Ma, D Zhao, Z Dou… - Journal of Infection, 2022 - Elsevier
Objectives High HIV-related mortality is mainly associated with severe immunosuppression
(CD4 count< 50 cells/μL) in people living with HIV (PLWH). This study intended to explore …

Changes in the small intestine mucosal immune barrier in Muscovy ducklings infected with Muscovy duck reovirus

Y Wu, Z Liu, E Zhu, M Li, H Jiang, Y Luo, Q Wang… - Veterinary …, 2019 - Elsevier
Muscovy duck reovirus (MDRV) causes serious immunodeficiency in the intestinal mucosa,
although the underlying histopathological mechanisms remain unclear. Thus, we …