Enhanced late Na and Ca currents as effective antiarrhythmic drug targets
HS Karagueuzian, A Pezhouman, M Angelini… - Frontiers in …, 2017 - frontiersin.org
While recent advances clarified the molecular and cellular modes of action of antiarrhythmic
drugs (AADs), their link to suppression of dynamical arrhythmia mechanisms remains only …
drugs (AADs), their link to suppression of dynamical arrhythmia mechanisms remains only …
Substrates and potential therapeutics of ventricular arrhythmias in heart failure
Heart failure (HF) is a clinical syndrome characterized by ventricular contractile dysfunction.
About 50% of death in patients with HF are due to fetal ventricular arrhythmias including …
About 50% of death in patients with HF are due to fetal ventricular arrhythmias including …
[HTML][HTML] Wanted: class VI antiarrhythmic drug action; new start for a rational drug therapy
HS Karagueuzian, U Klein - Journal of heart health, 2018 - ncbi.nlm.nih.gov
Since the discovery by a Dutch merchant in the early 20th Century that the drug quinine he
was taking to prevent malaria during his frequent trips to the West Indies also prevented his …
was taking to prevent malaria during his frequent trips to the West Indies also prevented his …
Triggered Ventricular Tachyarrhythmias Initiated by Enhanced Late Inward Na and Ca Currents: Novel Therapeutic Targets
HS Karagueuzian - Cardiac Mapping, 2019 - books.google.com
Enhanced late ICa‐L and late INa (INa‐L) emerge in congenital and acquired cardiac
diseases such as heart failure and cardiomyopathies. These pathological currents are …
diseases such as heart failure and cardiomyopathies. These pathological currents are …