A comprehensive approach to Parkinson's disease: addressing its molecular, clinical, and therapeutic aspects

M Muleiro Alvarez, G Cano-Herrera… - International journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a gradually worsening neurodegenerative disorder affecting the
nervous system, marked by a slow progression and varied symptoms. It is the second most …

Efficacy and safety of stereotactic radiosurgery with gamma knife machine in patients with essential tremor: a systematic review and single-arm meta-analysis

OR Gonçalves, HF Lima, CES Borges, ABS Júnior… - Neurosurgical …, 2024 - Springer
Essential tremor (ET) is identified as the most prevalent movement disorder, primarily
characterized by tremors in both upper extremities. The spectrum of surgical options for ET …

Gamma knife Thalamotomy for essential tremor: a retrospective analysis

S Horisawa, M Hayashi, N Tamura, K Kohara… - World Neurosurgery, 2023 - Elsevier
Background Gamma knife (GK) thalamotomy has been used as a treatment option for
essential tremor (ET). Numerous studies on GK use in ET treatment have reported more …

Surgical Treatments of Parkinson's Disease

AV Carpentier, MS Okun - Neurologic Clinics, 2025 - neurologic.theclinics.com
As Parkinson's disease (PD) progresses, patients treated with medication frequently
experience motor fluctuations, including “off” periods and dyskinesia, which can prove …

[HTML][HTML] Exceeding the Limits with Nutraceuticals: Looking Towards Parkinson's Disease and Frailty

M Montanari, NB Mercuri, G Martella - International Journal of Molecular …, 2024 - mdpi.com
One of the most pressing challenges facing society today is the rising prevalence of physical
and cognitive frailty. This geriatric condition makes older adults more vulnerable to disability …

Stereotactic radiosurgery in the treatment of essential tremor–a systematic review

M Bilski, K Szklener, S Szklener, A Rudzińska… - Frontiers in …, 2024 - frontiersin.org
Introduction Essential tremor (ET) is the most common movement disorder in adults, with an
estimated incidence of up to 1% of the population and 5% of people older than 65 years of …

Radiosurgical thalamotomy for the management of tremors: a systematic review and meta-analysis

ALL Larcipretti, FC Gomes, OC Udoma-Udofa… - Neurological …, 2025 - Springer
Medical treatment for tremors may include beta-blockers, primidone, dopaminergic, and
anticholinergic drugs but it frequently leads to pharmacoresistance. Therefore, surgical …

Role of Gamma Knife Radiosurgery in the Management of Functional Disorders–A Literature Review

S Verma, D Agrawal, M Singh - Neurology India, 2023 - journals.lww.com
Background: Role of radiosurgical lesioning in functional disorders has been restricted
because of development of deep brain stimulation (DBS) techniques. However, many …

Gamma knife versus linear accelerator thalamotomy for essential tremor and Parkinson's disease: A systematic review and meta-analysis

R Chintapalli, S Chang, T Kaprealian, R Savjani… - Journal of Clinical …, 2025 - Elsevier
Background Tremor, either in patients with Essential Tremor (ET) or Parkinson's disease
(PD), constitutes the most common movement disorder. Stereotactic radiosurgery using …

[HTML][HTML] Transcutaneous Kilohertz High-Frequency Alternating Current at 10 kHz for Upper-Limb Tremor in People with Parkinson's Disease: A Double-Blind …

JJ Fernández-Pérez, J Avendaño-Coy… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Preclinical studies have evidenced a peripheral nerve blockade
with kilohertz high-frequency alternating current (KHFAC) stimulation. It could have a …