Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

Our knowledge about the structure and function of the nonstructural proteins (nsps) encoded
by the arterivirus replicase gene has advanced in recent years. The continued …

Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, positive-
sense single-stranded RNA virus belonging to the Arteriviridae family. Arteriviruses and …

Programmed− 1 ribosomal frameshifting (− 1 PRF) is a widely used translational mechanism
facilitating the expression of two polypeptides from a single mRNA. Commonly, the ribosome …

The porcine reproductive and respiratory syndrome virus nsp1 is predicted to be auto-
cleaved from the replicase polyprotein into nsp1α and nsp1β subunits. In infected cells, we …

Zinc is indispensable to all forms of life as it is an essential component of many different
proteins involved in a wide range of biological processes. Not differently from other metals …

The immune surveillance system protects host cells from viral infection, and viruses have
evolved to escape this system for efficient proliferation in the host. Host cells produce …

Porcine reproductive and respiratory syndrome (PRRS) is an emerged disease of swine
characterized by negligible response of type I IFNs and viral persistence. We show that the …

Replication of eukaryotic positive-stranded RNA viruses is usually linked to the presence of
membrane-associated replicative organelles. The purpose of this review is to discuss the …

Papain-like cysteine peptidases form a big and highly diverse superfamily of proteins
involved in many important biological functions, such as protein turnover, deubiquitination …