Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …

History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Bioactive glasses (BGs) have been a focus of research for over five decades for several
biomedical applications. Although their use in bone substitution and bone tissue …

Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …

Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Highlights•TNBC is an unmet medical need with poor survival rates and no targeted
therapy.•TNBC resists conventional chemotherapy and surgical strategies.•A review of 121 …

This mini-review reports on the existing knowledge of the metabolic effects of palladium [Pd
(II)] complexes with potential anticancer activity, on cell lines and murine models. Most …

This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

This review focuses on studies of coordination and organometallic compounds as potential
chemotherapeutics against triple negative breast cancer (TNBC) which has one of the …