Purpose In multiple cell metazoans, the ability of polarized epithelial cells to convert to
motile mesenchymal cells in order to relocate to another location is governed by a unique …

Pathological cardiac hypertrophy is a key risk factor for the development of heart failure and
predisposes individuals to cardiac arrhythmia and sudden death. While physiological …

Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and was first
described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated …

Vascular endothelial growth factor (VEGF), a potent mitogen for vascular endothelium, is
expressed in malignant pleural mesothelioma (MM). The present report examines the effect …

Purpose: Mesothelin (MSLN) is a tumor-associated antigen, being investigated as a
biomarker and therapeutic target in malignant pleural mesothelioma (MPM). The biologic …

Abstract Background and Objective Numerous reports suggest that low‐power laser
irradiation (LPLI) is capable of affecting cellular processes in the absence of significant …

Abstract Fibroblast growth factor-2 (FGF-2) is a potent regulator of many cellular functions
and phenomena, including cell proliferation, differentiation, survival, adhesion, migration …

Therapeutic use of IL-2 can generate antitumor immunity; however, a variety of different
mechanisms have been reported. We injected IL-2 intratumorally (it) at different stages of …

Introduction Chronic inflammation plays a key role in the pathogenesis of malignant pleural
mesothelioma (MPM) as a result of asbestos exposure. Biomarkers of systemic inflammation …

Although mesothelioma is the consequence of a protracted immune response to asbestos
fibers and characterized by a clear immune infiltrate, novel immunotherapy approaches …