Low back pain (LBP) is a major cause of disability and imposes huge economic burdens on
human society worldwide. Among many factors responsible for LBP, intervertebral disc …

Intervertebral disc pathology is a common disorder that can be caused by genetic,
mechanical, and behavioral factors; however, it is possible to slow its progression. Although …

Background The incidence of intervertebral disc degeneration (IVDD) is a common
degenerative disease with inflammation, decreased autophagy, and progression of fibrosis …

(1) Background: The purpose of this review is to analyze domestic and foreign studies on the
role of collagen-encoding genes polymorphism in the development of intervertebral discs …

Intervertebral disc degeneration (IVDD), for which obesity and genetics are known risk
factors, is a chronic process that alters the structure and function of the intervertebral discs …

Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is
characterized by abnormal expression of extracellular matrix components such as collagen …

The aim of this study is to investigate the expression levels of genome-wide association
studies (GWAS)-identified variants near Gasdermin-C (GSDMC) and its association with …

Intervertebral disk degeneration (IDD) is a major cause of low back pain that becomes a
prevalent age‐related disease. However, the pathophysiological processes behind IDD are …

Background Current research on autophagy is mainly focused on intervertebral disc tissues
and cells, while there is few on human peripheral blood sample. therefore, this study …

Endoplasmic reticulum (ER) is an important player in various intracellular signaling
pathways that regulate cellular functions in many diseases. Intervertebral disc degeneration …