Precision risk analysis of cancer therapy with interactive nomograms and survival plots

GE Marai, C Ma, AT Burks, F Pellolio… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
We present the design and evaluation of an integrated problem solving environment for
cancer therapy analysis. The environment intertwines a statistical martingale model and a K …

The importance of dead material within a tumour on the dynamics in response to radiotherapy

TD Lewin, HM Byrne, PK Maini… - Physics in Medicine …, 2020 - iopscience.iop.org
In vivo tumours are highly heterogeneous, often comprising regions of hypoxia and necrosis.
Radiotherapy significantly alters the intratumoural composition. Moreover, radiation-induced …

Predicting radiotherapy patient outcomes with real-time clinical data using mathematical modelling

AP Browning, TD Lewin, RE Baker, PK Maini… - Bulletin of mathematical …, 2024 - Springer
Longitudinal tumour volume data from head-and-neck cancer patients show that tumours of
comparable pre-treatment size and stage may respond very differently to the same …

An overview on personalisation of radiotherapy prescriptions in locally advanced non-small cell lung cancer: Are we there yet?

S Barrett, GG Hanna, L Marignol - Radiotherapy and Oncology, 2018 - Elsevier
Standard of care radiotherapy in LA-NSCLC is 60–66 Gy in 30–33 fractions. However
outcomes for these patients are poor with 5-year survival in the range of 10–20 …