In vivo tumours are highly heterogeneous, often comprising regions of hypoxia and necrosis. Radiotherapy significantly alters the intratumoural composition. Moreover, radiation-induced …
Longitudinal tumour volume data from head-and-neck cancer patients show that tumours of comparable pre-treatment size and stage may respond very differently to the same …
S Barrett, GG Hanna, L Marignol - Radiotherapy and Oncology, 2018 - Elsevier
Standard of care radiotherapy in LA-NSCLC is 60–66 Gy in 30–33 fractions. However outcomes for these patients are poor with 5-year survival in the range of 10–20 …