Assessing the burden of Clostridium difficile infection in low-and middle-income countries

GA Roldan, AX Cui, NR Pollock - Journal of clinical microbiology, 2018 - Am Soc Microbiol
In contrast to the significant resources invested in the diagnosis and prevention of
Clostridium difficile infection (CDI) in resource-rich settings, in resource-limited settings …

The epidemiology of Clostridioides difficile infection in Brazil: A systematic review covering thirty years

CNR Trindade, RMCP Domingues, EO Ferreira - Anaerobe, 2019 - Elsevier
Clostridioides difficile is considered one of the main etiological agents of bacterial diarrhea
associated with the use of antibiotics. It is an important nosocomial pathogen and the main …

Multi-state survey of healthcare-associated infections in acute care hospitals in Brazil

CMCB Fortaleza, MC Padoveze, CRV Kiffer… - Journal of Hospital …, 2017 - Elsevier
Summary Background Healthcare-associated infections (HCAIs) challenge public health in
developing countries such as Brazil, which harbour social inequalities and variations in the …

Clinical epidemiology of Clostridium difficile infection among hospitalized patients with antibiotic-associated diarrhea in a university hospital of Brazil

GGL Cançado, ROS Silva, M Rupnik, AP Nader… - Anaerobe, 2018 - Elsevier
A cohort of 110 adult individuals was analyzed to compare clinical characteristics of
hospitalized patients who received antibiotics and developed Clostridium difficile infection …

Hypervirulent Clostridium difficile strain has arrived in Brazil

RN Pires, AA Monteiro, GZ Saldanha… - Infection Control & …, 2018 - cambridge.org
To the Editor—Clostridium difficile is an important cause of diarrhea in hospitals all over the
world. It is among the most common organisms related to healthcare-associated infections in …

Multicenter study of the epidemiology of Clostridioides difficile infection and recurrence in southern Brazil

AC Maestri, SM Raboni, HMP Morales, LF Ferrari… - Anaerobe, 2020 - Elsevier
Clostridioides (Clostridium) difficile is the main etiology underlying antibiotic-associated
diarrhea (AAD). Still, few Brazilian data are available on this infection. The aims of this …

[HTML][HTML] Burden of Clostridium (Clostridioides) difficile infection among patients in Western Asia: a systematic review and meta-analysis

Y Malekzadegan, M Halaji… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Clostridium difficile is the most common causes of hospital-acquired diarrhea
affecting particularly hospitalized patients globally. This organism has re-emerged in recent …

[HTML][HTML] Clostridium difficile contamination in retail meat products in Brazil

RN Pires, CFB Caurio, GZ Saldanha… - Brazilian Journal of …, 2018 - SciELO Brasil
Introduction Clostridium difficile is an important cause of diarrhoea, particularly in patients
receiving antibiotic therapy. Recent studies have shown that a substantial proportion of C …

Metronidazole for Treatment of Clostridioides difficile Infections in Brazil: A Single-Center Experience and Risk Factors for Mortality

JDF Alves, A Yamaguti, JS de Mendonça… - Antibiotics, 2022 - mdpi.com
We describe the epidemiology of C. difficile infections (CDIs) focused on treatment and
analyze the risk factors for mortality. This is a retrospective cohort study of CDI cases with a …

Clostridium difficile Infection

JH Shin, E Chaves-Olarte, CA Warren - Emerging Infections 10, 2016 - Wiley Online Library
The primary virulence factors that are known to cause clinical disease in Clostridium difficile
infection (CDI) are the two large toxins: TcdA (toxin A; 308 kDa) and TcdB (toxin B; 270 …