Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease

PJ Blanco, LO Müller, JD Spence - Stroke and vascular neurology, 2017 - svn.bmj.com
Rationale The role of hypertension in cerebral small vessel disease is poorly understood. At
the base of the brain (the 'vascular centrencephalon'), short straight arteries transmit blood …

A review on segmentation and modeling of cerebral vasculature for surgical planning

A Ajam, AA Aziz, VS Asirvadam, AS Muda, I Faye… - IEEE …, 2017 - ieeexplore.ieee.org
Visualization of cerebral blood vessels is vital for stroke diagnosis and surgical planning. A
suitable modality for the visualization of blood vessels is very important for the analysis of …

Coupling one-dimensional arterial blood flow to three-dimensional tissue perfusion models for in silico trials of acute ischaemic stroke

RM Padmos, TI Józsa, WK El-Bouri… - Interface …, 2021 - royalsocietypublishing.org
An acute ischaemic stroke is due to the sudden blockage of an intracranial blood vessel by
an embolized thrombus. In the context of setting up in silico trials for the treatment of acute …

A computational model applied to myocardial perfusion in the human heart: from large coronaries to microvasculature

S Di Gregorio, M Fedele, G Pontone, AF Corno… - Journal of …, 2021 - Elsevier
In this paper we present a mathematical and numerical model for human cardiac perfusion
which accounts for the different length scales of the vessels in the coronary tree. Epicardial …

Towards a glaucoma risk index based on simulated hemodynamics from fundus images

JI Orlando, J Barbosa Breda, K Van Keer… - … Image Computing and …, 2018 - Springer
Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its
major treatable risk factor is the intra-ocular pressure, although other biomarkers are being …

Approaches to vascular network, blood flow, and metabolite distribution modeling in brain tissue

V Kopylova, S Boronovskiy, Y Nartsissov - Biophysical Reviews, 2023 - Springer
The cardiovascular system plays a key role in the transport of nutrients, ensuring a
continuous supply of all cells of the body with the metabolites necessary for life. The blood …

Adaptive constrained constructive optimisation for complex vascularisation processes

GDM Talou, S Safaei, PJ Hunter, PJ Blanco - Scientific Reports, 2021 - nature.com
Mimicking angiogenetic processes in vascular territories acquires importance in the analysis
of the multi-scale circulatory cascade and the coupling between blood flow and cell function …

Blood flow distribution in an anatomically detailed arterial network model: criteria and algorithms

PJ Blanco, SM Watanabe, EA Dari… - … and modeling in …, 2014 - Springer
Abstract Development of blood flow distribution criteria is a mandatory step toward
developing computational models and numerical simulations of the systemic circulation. In …

Brain venous haemodynamics, neurological diseases and mathematical modelling. A review

EF Toro - Applied Mathematics and Computation, 2016 - Elsevier
Abstract Behind Medicine (M) is Physiology (P), behind Physiology is Physics (P) and
behind Physics is always Mathematics (M), for which I expect that the symmetry of the …

Non‐invasive coronary CT angiography‐derived fractional flow reserve: a benchmark study comparing the diagnostic performance of four different computational …

JM Carson, S Pant, C Roobottom… - … journal for numerical …, 2019 - Wiley Online Library
Non‐invasive coronary computed tomography (CT) angiography‐derived fractional flow
reserve (cFFR) is an emergent approach to determine the functional relevance of obstructive …