The increased prevalence of age-related comorbidities and mortality is worrisome in ageing
HIV-infected patients. Here, we aim to analyse the different ageing mechanisms with regard …

Skeletal muscle maintains posture and enables movement by converting chemical energy
into mechanical energy, further contributing to basal energy metabolism. Thyroid hormones …

Ageing appears to be a nearly universal feature of life, ranging from unicellular
microorganisms to humans. Longevity depends on the maintenance of cellular functionality …

Aging predisposes to hepatic dysfunction and inflammation that can contribute to the
development of non-alcoholic fatty liver disease. Spirulina, a cyanobacterium used as a food …

Maximal longevity of endotherms has long been considered to increase with decreasing
specific metabolic rate, and thus with increasing body mass. Using a dataset of over 700 …

Small heat shock proteins (sHSPs) are gatekeepers of cellular homeostasis across species,
preserving proteome integrity under stressful conditions. Nonetheless, recent evidence …

Marine ecosystems are both stressed and threatened by pesticides that are used on land.
Nevertheless, research on the impact of pesticides on coral reefs and the underlying …

The metabolic and endocrine functions of adipose tissue and the ability of organisms to
cope with cellular stress have a direct impact on physiological ageing and the aetiology of …

Selection in novel environments can lead to a coordinated evolutionary response across a
suite of characters. Environmental conditions can also potentially induce changes in the …

Understanding the complex biological process of aging is of great value, especially as it can
help develop therapeutics to prolong healthy life. Predicting biological age from gene …