Sphingolipid organization in biomembranes: what physical studies of model membranes reveal

RE Brown - Journal of cell science, 1998 - journals.biologists.com
Recent cell biological studies suggest that sphingolipids and cholesterol may cluster in
biomembranes to form raft-like microdomains. Such lipid domains are postulated to function …

Mechanisms and consequences of cellular cholesterol exchange and transfer

MC Phillips, WJ Johnson, GH Rothblat - Biochimica et Biophysica Acta …, 1987 - Elsevier
Unesterified (free) cholesterol is essential for cell viability with a critical function being the
maintenance of appropriate membrane structure (for reviews, see Refs. 1-3). Cells can …

Fluorescence method for measuring the kinetics of fusion between biological membranes

D Hoekstra, T De Boer, K Klappe, J Wilschut - Biochemistry, 1984 - ACS Publications
Dick Hoekstra,* Tiny de Boer, Karin Klappe, and Jan Wilschut abstract: An assay is
presented that allows continuous and sensitive monitoring of membrane fusion in both …

Liposomes: preparation, characterization, and preservation

D Lichtenberg, Y Barenholz - Methods Biochem. Anal, 1988 - books.google.com
340 DOV LICHTENBERG AND YECHEZKEL BARENHOLZ edited by Gregoriadis (1984),
and most recently in a special issue of Chemistry and Physics of Lipids entitled …

An update of the enzymology and regulation of sphingomyelin metabolism

AH Merrill Jr, DD Jones - Biochimica et Biophysica Acta (BBA)-Lipids and …, 1990 - Elsevier
Sphingomyelin is found in plasma membranes and related organelles (such as endocytic
vesicles and lysosomes) of all tissues, as well as in lipoproteins. Abnormalities in …

Defining lipid transport pathways in animal cells

RE Pagano, RG Sleight - Science, 1985 - science.org
A new technique for studying the metabolism and intracellular transport of lipid molecules in
living cells based on the use of fluorescent lipid analogs is described. The cellular …

Sphingomyelin and cholesterol: from membrane biophysics and rafts to potential medical applications

Y Barenholz - Membrane Dynamics and Domains: Subcellular …, 2004 - Springer
The preferential sphingomyelin—cholesterol interaction which results from the structure and
the molecular properties of these two lipids seems to be the physicochemical basis for the …

Kinetics and structural aspects of reconstitution of phosphatidylcholine vesicles by dilution of phosphatidylcholine-sodium cholate mixed micelles

S Almog, T Kushnir, S Nir, D Lichtenberg - Biochemistry, 1986 - ACS Publications
Clinical Toxicology and Pharmacology, Chaim Sheba Medical Center, Tel Hashomer, Israel,
and The Seagram Center for Soil and Water Sciences, Faculty of Agriculture, Hebrew …

Use of cyclodextrin for AFM monitoring of model raft formation

MC Giocondi, PE Milhiet, P Dosset, C Le Grimellec - Biophysical journal, 2004 - cell.com
The lipid rafts membrane microdomains, enriched in sphingolipids and cholesterol, are
implicated in numerous functions of biological membranes. Using atomic force microscopy …

Spontaneous lipid transfer between organized lipid assemblies

RF Brown - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1992 - Elsevier
With the recognition that lipids are not only key structural elements of membranes, but often
function ('orrc~ p, md~: n¢ c Io: R+ I:,.| lmv, n. Itormcl Inslilul¢. 8111 I¢~ th Ave NE. Austin. MN …