Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with …

CW Grant, AR Wilton, R Kaddurah-Daouk… - Frontiers in …, 2022 - frontiersin.org
Background: Individuals with major depressive disorder (MDD) and a lifetime history of
attempted suicide demonstrate lower antidepressant response rates than those without a …

Mental health difficulties related to suicidal behavior in adolescents: the moderating role of self-esteem

U de la Barrera, I Montoya-Castilla… - Archives of Suicide …, 2022 - Taylor & Francis
Objective The objective was to analyze the moderating effect of self-esteem on the
relationship between mental health difficulties and suicidal behavior in adolescence …

Leptin and leptin receptor gene polymorphisms and depression treatment response

IM Tavast, A Solismaa, LP Lyytikäinen… - Acta …, 2024 - cambridge.org
Objective: Associations between leptin (LEP) and leptin receptor (LEPR) gene
polymorphisms and mood disorders have been found but not yet confirmed in multiple …

The identification of key genes and pathways in polycystic ovary syndrome by bioinformatics analysis of next-generation sequencing data

V Alur, B Vastrad, V Raju, C Vastrad… - Middle East Fertility …, 2024 - Springer
Background Polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder. The
specific molecular mechanism of PCOS remains unclear. The aim of this study was to apply …

Association Between the A118G Polymorphism of the OPRM1 Gene and Suicidal Depression in a Large Cohort of Outpatients with Depression

B Nobile, E Olie, N Ramoz, J Dubois… - Neuropsychiatric …, 2021 - Taylor & Francis
Background Growing evidences suggest that depression with suicidal ideation (SI) could be
a specific phenotype with its own characteristics. Moreover, opioid system deregulation …

The Identification of Key Genes and Biological Pathways in Polycystic Ovary Syndrome and its Complications by Next Generation Squancing (NGS) and …

B Vastrad, C Vastrad - bioRxiv, 2023 - biorxiv.org
Polycystic ovary syndrome (PCOS) is is associated with infertility, obesity, insulin resistance,
hyperinsulinemia, type 2 diabetes mellitus, hypertension, cardiovascular problems …

[HTML][HTML] Genetic Variations and Serum Levels of Leptin and Ghrelin in Autism Spectrum Disorder

ÖN Yazici, N Şahin, Ç Özdemir… - Psychiatry and …, 2024 - pmc.ncbi.nlm.nih.gov
Background: This study aims to examine leptin and ghrelin gene polymorphisms and serum
levels in children with autism spectrum disorder (ASD). Methods: The study comprised a …

Genetics of adolescent suicide: a literature review

A Mathew, N Nebhinani, S Begum… - Journal of Indian …, 2021 - journals.sagepub.com
Adolescent suicidal behavior is a global public health issue; however, genetic studies are
sparse and diverse. A review of the current knowledge on the genetics of adolescent suicide …