The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules,
have mainly been explored in free solution. We report on the design, synthesis, and …

The Rhodopsin family of G-protein–coupled receptors (GPCRs) comprises the targets of
nearly a third of all pharmaceuticals. Despite structural water present in GPCR X-ray …

Nuclear magnetic resonance (NMR) spectroscopy is a principal well-established technique
for analysis of chemical, biological, food and environmental samples. This article provides …

Inward proton pumping is a relatively new function for microbial rhodopsins, retinal-binding
light-driven membrane proteins. So far, it has been demonstrated for two unrelated …

The cannabinoid type 1 and 2 G-protein-coupled receptors are currently important
pharmacological targets with significant drug discovery potential. These receptors have …

Preparation and storage of functional membrane proteins such as G-protein-coupled
receptors (GPCRs) are crucial to the processes of drug delivery and discovery. Here, we …

Rhodopsin mediates the scotopic vision of vertebrates under low light conditions and is the
archetype for the G-protein-coupled receptor (GPCR) proteins that regulate many of the vital …

Here, we summarize the procedures of preparing G protein-coupled receptors (GPCRs) for
NMR investigation in sufficient quantity, with the necessary isotopic labeling and their …

The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules,
have mainly been explored in free solution. Here we report on the design, synthesis, and …

My thesis is focused on role of soft matter (membrane lipids plus water) in G-protein coupled
receptor (GPCR) activation. Notably GPCRs are one of the hot topics that have attracted …