Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …

Angiogenesis is an important component in the development of thyroid goitre. Vascular
endothelial growth factor (VEGF) represents a family of specific endothelial cell mitogens …

The BCL2 protooncogene encodes an inner mitochondrial membrane protein that blocks
programmed cell death. BCL2 was isolated from the chromosomal breakpoint of follicular B …

The global effort to prevent iodine deficiency disorders through iodine supplementation,
such as universal salt iodization, has achieved impressive progress during the last few …

Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex
disease, with a strong genetic component. To date, significant progress has been made …

Micronutrients, mostly iodine and selenium, are required for thyroid hormone synthesis and
function. Iodine is an essential component of thyroid hormones and its deficiency is …

Thyroid toxicity of iodide excess has been demonstrated in animals fed with an iodide-rich
diet; in vitro iodide is cytotoxic, inhibits cell growth, and induces morphological changes in …

The current iodine status and the impact of silent iodine prophylaxis on the prevalence of
autoimmune thyroiditis among schoolchildren in a formerly iodine-deficient community in …

Like most autoimmune diseases of humans, chronic lymphocytic (Hashimoto's) thyroiditis
results from the combination of a genetic predisposition and an environmental trigger. A …

Subclinical thyroid disease is defined biochemically by an abnormal thyrotropin (TSH) level
and normal serum-free thyroxine level. The prevalence of this condition varies according to …