Multimodality advanced cardiovascular and molecular imaging for early detection and monitoring of cancer therapy-associated cardiotoxicity and the role of artificial …

JM Kwan, EK Oikonomou, ML Henry… - Frontiers in …, 2022 - frontiersin.org
Cancer mortality has improved due to earlier detection via screening, as well as due to novel
cancer therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitions …

PET tracers for imaging cardiac function in cardio-oncology

JM Kelly, JW Babich - Current cardiology reports, 2022 - Springer
Abstract Purpose of Review Successful treatment of cancer can be hampered by the
attendant risk of cardiotoxicity, manifesting as cardiomyopathy, left ventricle systolic …

Molecular imaging biomarkers in cardiooncology: a view on established technologies and future perspectives

D Kersting, IA Mavroeidi, S Settelmeier… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Novel therapeutic options have significantly improved survival and long-term outcomes in
many cancer entities. Unfortunately, this improvement in outcome is often accompanied by …

Nuclear medicine in the assessment and prevention of cancer therapy-related cardiotoxicity: prospects and proposal of use by the European Association of Nuclear …

M Totzeck, N Aide, J Bauersachs, J Bucerius… - European journal of …, 2023 - Springer
Cardiotoxicity may present as (pulmonary) hypertension, acute and chronic coronary
syndromes, venous thromboembolism, cardiomyopathies/heart failure, arrhythmia, valvular …

Physicochemical characterization and potential cancer therapy applications of hydrogel beads loaded with doxorubicin and GaOOH nanoparticles

A Żmuda, W Kamińska, M Bartel, K Głowacka… - Scientific Reports, 2024 - nature.com
A new type of hybrid polymer particles capable of carrying the cytostatic drug doxorubicin
and labeled with a gallium compound was prepared. These microparticles consist of a core …

Chondro-inductive hyaluronic acid/chitosan coacervate-based scaffolds for cartilage tissue engineering

ÖK Acar, S Bedir, AB Kayitmazer, GT Kose - International Journal of …, 2021 - Elsevier
Injuries related to articular cartilage are among the most challenging musculoskeletal
problems because of poor repair capacity of this tissue. The lack of efficient treatments for …

Doxorubicin nanomedicine based on ginsenoside Rg1 with alleviated cardiotoxicity and enhanced antitumor activity

C Li, X Gou, H Gao - Nanomedicine, 2021 - Taylor & Francis
Aim: The authors aimed to develop Dox@ Rg1 nanoparticles with decreased cardiotoxicity
to expand their application in cancer. Materials & methods: Dox@ Rg1 nanoparticles were …

Effects of N‐acetyl‐L‐cysteine against apical periodontitis in rats with adriamycin‐induced cardiomyopathy and nephropathy

AÖ Şehirli, U Aksoy, A Sibai, K Orhan… - International …, 2024 - Wiley Online Library
Aim This study aimed to investigate the potential protective effects of N‐acetyl‐L‐cysteine
(NAC) against apical periodontitis (AP) in rats with adriamycin (ADR)‐induced kidney and …

[HTML][HTML] Galuminox: Preclinical validation of a novel PET tracer for non-invasive imaging of oxidative stress in vivo

J Sivapackiam, F Liao, D Zhou, KI Shoghi, RJ Gropler… - Redox Biology, 2020 - Elsevier
Overproduction of reactive oxygen species (ROS) is a well-established indicator of ongoing
tissue inflammation. However, there is a scarcity of molecular imaging probes capable of …

PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study

FJ Detmer, NM Alpert, SH Moon, M Dhaynaut… - Scientific Reports, 2022 - nature.com
Mitochondrial dysfunction plays a key role in doxorubicin-induced cardiotoxicity (DIC). In this
proof-of-principle study, we investigated whether PET mapping of cardiac membrane …