Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

Methods: We performed an extensive literature search in Google Scholar and Pub Med
databases that were published between December 7, 1999 and January 9, 2018 in …

Importance Opioids are frequently prescribed to children and adolescents after surgery.
Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based …

Use of prescription stimulants by normal healthy individuals to enhance cognition is said to
be on the rise. Who is using these medications for cognitive enhancement, and how …

Opioid abuse has increased in the last decade, primarily as a result of increased access to
prescription opioids. Physicians are also increasingly administering opioid analgesics for …

Therapeutic opioid use has increased substantially, specifically of Schedule II drugs. Apart
from lack of effectiveness (except for short-term, acute pain) there are multiple adverse …

Study objective Increasing opioid prescribing has been linked to an epidemic of opioid
misuse. Our objective is to synthesize the available evidence about patient-, prescriber …

Most people who are regular consumers of psychoactive drugs are not drug addicts, nor will
they ever become addicts. In neurobiological theories, non-addictive drug consumption is …

The purpose was to systematically review the global trends and factors influencing self-
medication (SM) among adolescents. Databases (Medline/Pubmed, Ingenta, Cochrane …

Background: Opioid abuse has continued to increase at an alarming rate since our last
opioid guidelines were published in 2005. Available evidence suggests a continued wide …