[HTML][HTML] Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder
H Guo, Y Ouyang, H Yin, H Cui, H Deng, H Liu, Z Jian… - Redox biology, 2022 - Elsevier
Copper (Cu) is a necessary micronutrient at lower concentration, while excessive Cu
exposure or Cu homeostasis disorders can lead to toxicity. The mechanism of male …
exposure or Cu homeostasis disorders can lead to toxicity. The mechanism of male …
Synergistic effect of PS-MPs and Cd on male reproductive toxicity: Ferroptosis via Keap1-Nrf2 pathway
It has been wildly reported that microplastics (MPs) can adsorb heavy metals and act as
carriers for their transport into organisms. However, the combined toxicity of MPs and heavy …
carriers for their transport into organisms. However, the combined toxicity of MPs and heavy …
The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and …
R Heidari - Toxicology, 2019 - Elsevier
Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …
[HTML][HTML] Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic …
R Heidari, H Niknahad, A Sadeghi… - Biomedicine & …, 2018 - Elsevier
Betaine is a derivative of the amino acid glycine widely investigated for its hepatoprotective
properties against alcoholism. The protective properties of betaine in different other …
properties against alcoholism. The protective properties of betaine in different other …
[HTML][HTML] The research progress on the impact of antibiotics on the male reproductive system
L Hou, Y Fu, C Zhao, L Fan, H Hu, S Yin - Environment International, 2024 - Elsevier
Antibiotics are extensively utilized in the livestock and poultry industry and can accumulate
in animals and the environment, leading to potential health risks for humans via food and …
in animals and the environment, leading to potential health risks for humans via food and …
The mechanisms of arsenic-induced ovotoxicity, ultrastructural alterations, and autophagic related paths: An enduring developmental study in folliculogenesis of mice
Arsenic (As) exerts a wide range of adverse effects on biological systems, including the
reproductive organs in males and females. However, the mechanisms of As-induced …
reproductive organs in males and females. However, the mechanisms of As-induced …
The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity
A Ahmadi, H Niknahad, H Li, A Mobasheri… - Toxicology Letters, 2021 - Elsevier
The cholestatic liver injury could occur in response to a variety of diseases or xenobiotics.
Although cholestasis primarily affects liver function, it has been well-known that other organs …
Although cholestasis primarily affects liver function, it has been well-known that other organs …
Glycine protects the male reproductive system against lead toxicity via alleviating oxidative stress, preventing sperm mitochondrial impairment, improving kinematics of …
Lead (Pb) is a highly toxic heavy metal widely dispersed in the environment because of
human industrial activities. Many studies revealed that Pb could adversely affect several …
human industrial activities. Many studies revealed that Pb could adversely affect several …
Carnosine and histidine supplementation blunt lead-induced reproductive toxicity through antioxidative and mitochondria-dependent mechanisms
Lead (Pb)-induced reproductive toxicity is a well-characterized adverse effect associated
with this heavy metal. It has been found that Pb exposure is associated with altered …
with this heavy metal. It has been found that Pb exposure is associated with altered …
Cu-induced spermatogenesis disease is related to oxidative stress-mediated germ cell apoptosis and DNA damage
H Guo, Y Ouyang, J Wang, H Cui, H Deng… - Journal of Hazardous …, 2021 - Elsevier
Copper is considered as an indispensable trace element for living organisms. However,
over-exposure to Cu can lead to adverse health effects on human. In this study, CuSO 4 …
over-exposure to Cu can lead to adverse health effects on human. In this study, CuSO 4 …