Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

Neuronal microenvironment imbalance is associated with successive and irreversible
pathophysiological changes and insufficient functional restoration after peripheral nerve …

Peripheral nerve injury (PNI) is currently recognized as one of the most significant public
health issues and affects the general well‐being of millions of individuals worldwide …

Peripheral nerve injury is a complex condition with a variety of signs and symptoms such as
numbness, tingling, jabbing, throbbing, burning or sharp pain. Peripheral nerves are fragile …

Skeletal tissue is highly innervated. Although different types of nerves have been recently
identified in the bone, the crosstalk between bone and nerves remains unclear. In this …

The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result
in a significant loss of sensory or motor function. Restoration of the injured nerves requires a …

Peripheral nerve injuries (PNI) resulting from trauma can be severe and permanently
debilitating. Despite the armamentarium of meticulous microsurgical repair techniques that …

A neuroimmune crosstalk is involved in somatic and visceral pathological pain including
inflammatory and neuropathic components. Apart from microglia essential for spinal and …

Resident and inflammatory macrophages are essential effectors of the innate immune
system. These cells provide innate immune defenses and regulate tissue and organ …