Sex matters: a comprehensive comparison of female and male hearts

SR St. Pierre, M Peirlinck, E Kuhl - Frontiers in physiology, 2022 - frontiersin.org
Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …

Molecular imaging

R Weissleder, U Mahmood - Radiology, 2001 - pubs.rsna.org
The term molecular imaging can be broadly defined as the in vivo characterization and
measurement of biologic processes at the cellular and molecular level. In contradistinction to …

Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-α

T Kubota, CF McTiernan, CS Frye, SE Slawson… - Circulation …, 1997 - Am Heart Assoc
The failing human heart expresses tumor necrosis factor-α (TNF-α). However, its
pathophysiological significance is not clear. We previously reported that robust …

Echocardiography in mice

S Gao, D Ho, DE Vatner… - Current protocols in mouse …, 2011 - Wiley Online Library
Murine models have been utilized with increasing frequency mainly due to availability of
genetically engineered models. With advancement in high spatial and temporal resolution …

Compound loss of muscleblind‐like function in myotonic dystrophy

KY Lee, M Li, M Manchanda, R Batra… - EMBO molecular …, 2013 - embopress.org
Myotonic dystrophy (DM) is a multi‐systemic disease that impacts cardiac and skeletal
muscle as well as the central nervous system (CNS). DM is unusual because it is an RNA …

Cyclin A2 mediates cardiomyocyte mitosis in the postmitotic myocardium

HW Chaudhry, NH Dashoush, H Tang, L Zhang… - Journal of Biological …, 2004 - ASBMB
Cell cycle withdrawal limits proliferation of adult mammalian cardiomyocytes. Therefore, the
concept of stimulating myocyte mitotic divisions has dramatic implications for cardiomyocyte …

Micro‐CT with respiratory and cardiac gating: Micro‐CT with respiratory and cardiac gating

C Badea, LW Hedlund, GA Johnson - Medical physics, 2004 - Wiley Online Library
Cardiopulmonary imaging in rodents using micro‐computed tomography (CT) is a
challenging task due to both cardiac and pulmonary motion and the limited fluence rate …

Developmental changes of cardiac function and mass assessed with MRI in neonatal, juvenile, and adult mice

F Wiesmann, J Ruff, KH Hiller… - American Journal …, 2000 - journals.physiology.org
Cardiovascular transgenic mouse models with an early phenotype or even premature death
require noninvasive imaging methods that allow for accurate visualization of cardiac …

Challenges in small animal noninvasive imaging

RS Balaban, VA Hampshire - ILAR journal, 2001 - academic.oup.com
The current status and challenges of small animal noninvasive imaging are briefly reviewed.
The advantages of noninvasive studies on living animals versus postmortem studies are …

Dobutamine-stress magnetic resonance microimaging in mice: acute changes of cardiac geometry and function in normal and failing murine hearts

F Wiesmann, J Ruff, S Engelhardt, L Hein… - Circulation …, 2001 - Am Heart Assoc
The aim of this study was to assess the capability of MRI to characterize systolic and
diastolic function in normal and chronically failing mouse hearts in vivo at rest and during …