Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies

RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …

In vivo magnetic resonance spectroscopy of GABA: a methodological review

NAJ Puts, RAE Edden - Progress in nuclear magnetic resonance …, 2012 - Elsevier
Conclusion MRS has become established as a robust and powerful tool for the investigation
of the inhibitory neurotransmitter GABA. This is a significant success, given the significant …

Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels

F Gao, RAE Edden, M Li, NAJ Puts, G Wang, C Liu… - Neuroimage, 2013 - Elsevier
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain.
Although measurements of GABA levels in vivo in the human brain using edited proton …

Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics

B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2016 - Taylor & Francis
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …

[HTML][HTML] Neuroimaging in social anxiety disorder: a systematic review of the literature

MC Freitas-Ferrari, JEC Hallak, C Trzesniak… - Progress in Neuro …, 2010 - Elsevier
Brain imaging techniques allow the in vivo evaluation of the human brain, leading to a better
understanding of its anatomical, functional and metabolic substrate. The aim of this current …

Early-life lead exposure induces long-term toxicity in the central nervous system: From zebrafish larvae to juveniles and adults

Z Wang, H Zhao, Y Xu, J Zhao, Z Song, Y Bi, Y Li… - Science of the Total …, 2022 - Elsevier
Lead induced neurotoxicity has been extensively investigated. However, the potential
connections between early-life lead exposure and the frequently observed aberrant …

PTSD: from neurobiology to pharmacological treatments

B Kelmendi, TG Adams, S Yarnell… - European journal of …, 2016 - Taylor & Francis
Posttraumatic stress disorder (PTSD) is a chronic debilitating psychiatric disorder
characterized by symptoms of re-experience, avoidance, and hyperarousal that can arise …

Ketamine for social anxiety disorder: a randomized, placebo-controlled crossover trial

JH Taylor, A Landeros-Weisenberger… - …, 2018 - nature.com
Many patients with social anxiety disorder (SAD) experience inadequate symptom relief from
available treatments. Ketamine is a potent N-methyl-D-aspartate receptor antagonist with a …

Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder

RB Price, DC Shungu, X Mao, P Nestadt, C Kelly… - Biological …, 2009 - Elsevier
BACKGROUND: Significant alterations in γ-aminobutyric acid (GABA) and glutamate levels
have been previously reported in symptomatic and remitted major depressive disorder …

Frontal lobe γ-aminobutyric acid levels during adolescence: associations with impulsivity and response inhibition

MM Silveri, JT Sneider, DJ Crowley, MJ Covell… - Biological …, 2013 - Elsevier
Background The brain undergoes major remodeling during adolescence, resulting in
improved cognitive control and decision-making and reduced impulsivity, components of …