Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target

E Capone, S Iacobelli, G Sala - Journal of translational medicine, 2021 - Springer
The lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a secreted,
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …

The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system

MR Sarrias, J Gronlund, O Padilla… - Critical Reviews™ in …, 2004 - dl.begellhouse.com
ABSTRACT The Scavenger Receptor Cysteine-Rich (SRCR) domain is an ancient and
highly conserved protein module of~ 100− 110 amino acids, which defines a superfamily …

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

C Gutmann, K Takov, SA Burnap, B Singh, H Ali… - Nature …, 2021 - nature.com
Prognostic characteristics inform risk stratification in intensive care unit (ICU) patients with
coronavirus disease 2019 (COVID-19). We obtained blood samples (n= 474) from …

Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma

A Chen, Y Jiang, Z Li, L Wu, U Santiago… - The Journal of …, 2021 - Am Soc Clin Investig
Glioblastoma (GBM), the most common and lethal primary brain tumor, with a median
survival rate of only 15 months, remains incurable despite intensive multimodal treatment of …

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach* S

M Grønborg, TZ Kristiansen, A Iwahori, R Chang… - Molecular & Cellular …, 2006 - ASBMB
Quantitative proteomics can be used as a screening tool for identification of differentially
expressed proteins as potential biomarkers for cancers. Candidate biomarkers from such …

Concentrations of galectin-3 in the sera of normal controls and cancer patients

I Iurisci, N Tinari, C Natoli, D Angelucci, E Cianchetti… - Clinical cancer …, 2000 - AACR
Galectin-3, a member of the β-galactoside-binding animal lectins, has been implicated in
tumor invasion and metastasis. Using an immunoligand assay, we assessed the circulating …

Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy …

A de Menezes-Neto, MJF Sáez… - Journal of …, 2015 - Taylor & Francis
Plasma-derived vesicles hold a promising potential for use in biomedical applications. Two
major challenges, however, hinder their implementation into translational tools:(a) the …

DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3–26.1 is deleted in malignant brain tumours

J Mollenhauer, S Wiemann, W Scheurlen, B Korn… - Nature …, 1997 - nature.com
Loss of sequences from human chromosome 10q has been associated with the progression
of human cancer. Medulloblastoma and glioblastoma multiforme are the most common …

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

SR Langley, K Willeit, A Didangelos… - The Journal of …, 2017 - Am Soc Clin Investig
BACKGROUND. The identification of patients with high-risk atherosclerotic plaques prior to
the manifestation of clinical events remains challenging. Recent findings question histology …

Changes in the chemical barrier composition of tears in Alzheimer's disease reveal potential tear diagnostic biomarkers

G Kalló, M Emri, Z Varga, B Ujhelyi, J Tőzsér, A Csutak… - PloS one, 2016 - journals.plos.org
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, with
increasing prevalence affecting millions of people worldwide. Currently, only autopsy is able …