Nanostructured antimicrobial peptides: The last push towards clinics

JV Carratalá, N Serna, A Villaverde, E Vázquez… - Biotechnology …, 2020 - Elsevier
Peptide drugs hold great potential for the treatment of infectious diseases due to their
unconventional mechanisms of action, biocompatibility, biodegradability and ease of …

Nanostructured antimicrobial peptides: crucial steps of overcoming the bottleneck for clinics

Z Yang, S He, H Wu, T Yin, L Wang… - Frontiers in Microbiology, 2021 - frontiersin.org
The security issue of human health is faced with dispiriting threats from multidrug-resistant
bacteria infections induced by the abuse and misuse of antibiotics. Over decades, the …

Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Advancement of nanoscience in development of conjugated drugs for enhanced disease prevention

P Taneja, S Sharma, VB Sinha, AK Yadav - Life sciences, 2021 - Elsevier
Nanoscience and nanotechnology is a recently emerging and rapid developing field of
science and has also been explored in the fields of Biotechnology and Medicine …

Recombinant Proteins for Assembling as Nano-and Micro-Scale Materials for Drug Delivery: A Host Comparative Overview

JL Corchero, MTP Favaro, M Márquez-Martínez… - Pharmaceutics, 2023 - mdpi.com
By following simple protein engineering steps, recombinant proteins with promising
applications in the field of drug delivery can be assembled in the form of functional materials …

Bacteriophages in nature: recent advances in research tools and diverse environmental and biotechnological applications

M Bisen, K Kharga, S Mehta, N Jabi… - Environmental Science and …, 2024 - Springer
Bacteriophages infect and replicate within bacteria and play a key role in the environment,
particularly in microbial ecosystems and bacterial population dynamics. The increasing …

The poly-histidine tag H6 mediates structural and functional properties of disintegrating, protein-releasing inclusion bodies

JM Sánchez, JV Carratalá, N Serna, U Unzueta… - Pharmaceutics, 2022 - mdpi.com
The coordination between histidine-rich peptides and divalent cations supports the
formation of nano-and micro-scale protein biomaterials, including toxic and non-toxic …

Engineering Matrix-Free Drug Protein Nanoparticles with Promising Penetration through Biobarriers for Treating Corneal Neovascularization

H Xu, B Mao, S Ni, X Xie, S Tang, Y Wang, X Zan… - ACS …, 2024 - ACS Publications
Protein drugs have been widely used in treating various clinical diseases because of their
high specificity, fewer side effects, and favorable therapeutic effect, but they greatly suffer …

Hybrid Micro-/Nanoprotein Platform Provides Endocrine-like and Extracellular Matrix-like Cell Delivery of Growth Factors

H López-Laguna, PM Tsimbouri… - … Applied Materials & …, 2024 - ACS Publications
Protein materials are versatile tools in diverse biomedical fields. Among them, artificial
secretory granules (SGs), mimicking those from the endocrine system, act as mechanically …

Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling

H López-Laguna, A Rueda… - ACS Sustainable …, 2023 - ACS Publications
Nanoscale protein materials show increasing applications in biotechnology and
biomedicine, addressing catalysis, drug delivery, or tissue engineering. Although protein …