Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Chronic glaucoma is a multifactorial disease among which oxidative stress may play a major
pathophysiological role. We conducted a systematic review and meta-analysis to evaluate …

Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …

Purpose.: To investigate the effect of K-115, a novel Rho kinase (ROCK) inhibitor, on retinal
ganglion cell (RGC) survival in an optic nerve crush (NC) model. Additionally, to determine …

Glaucoma is one of the leading causes of blindness. Therapies available suffer from several
drawbacks including low bioavailability, repeated administration and poor patient …

Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Cataract and glaucoma are the major causes of severe visual loss and blindness in older
adults. This review article describes the currently available basic and clinical evidence …

Abstract NF‐E2 related factor 2 (Nrf2) is a key transcription factor that plays a pivotal role in
endogenous protection against oxidative stress. However, the role of Nrf2 in visual disorders …

Background: The aim of is to determine the association of vitamins with glaucoma by
performing a systematic review and meta-analyses. Methods: Studies on the relation of …