Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

SGLT2 inhibitors: from glucose-lowering to cardiovascular benefits

A Preda, F Montecucco, F Carbone… - Cardiovascular …, 2024 - academic.oup.com
An increasing number of individuals are at high risk of type 2 diabetes (T2D) and its
cardiovascular complications, including heart failure (HF), chronic kidney disease (CKD) …

SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids

S Wu, C Li, Y Li, J Liu, C Rong, H Pei, X Li… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: The excretion and absorption of uric acid (UA) by the kidneys helps regulate
serum UA levels. GLUT9, encoded by SLC2A9, is mainly expressed in the renal tubules …

A Comparative Study of Risk Factors and Prognosis in Young and Elderly Patients with Acute ST-Segment Elevation Myocardial Infarction

S Wang, D Ruan, M Zhang, H Zhou… - Journal of Clinical …, 2024 - ojs.bbwpublisher.com
Objective: To investigate the differences in risk factors and prognosis between young and
elderly patients with acute ST-segment elevation myocardial infarction (STEMI) to provide a …