Parkinson's disease: etiology, neuropathology, and pathogenesis

A Kouli, KM Torsney, WL Kuan - Exon Publications, 2018 - exonpublications.com
Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …

Epidemiology and etiology of Parkinson's disease: a review of the evidence

K Wirdefeldt, HO Adami, P Cole, D Trichopoulos… - European journal of …, 2011 - Springer
The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

Incidence of Parkinson disease in North America

AW Willis, E Roberts, JC Beck, B Fiske, W Ross… - npj Parkinson's …, 2022 - nature.com
Parkinson disease (PD) is the second most common age-related neurodegenerative
condition diagnosed in North America. We recently demonstrated, using multiple …

Prevalence of Parkinson's disease across North America

C Marras, JC Beck, JH Bower, E Roberts, B Ritz… - NPJ Parkinson's …, 2018 - nature.com
Estimates of the prevalence of Parkinson's disease in North America have varied widely and
many estimates are based on small numbers of cases and from small regional …

The current and projected economic burden of Parkinson's disease in the United States

SL Kowal, TM Dall, R Chakrabarti… - Movement …, 2013 - Wiley Online Library
Parkinson's disease (PD), following Alzheimer's disease, is the second‐most common
neurodegenerative disorder in the United States. A lack of treatment options for changing …

Epidemiology of Parkinson's disease

LML De Lau, MMB Breteler - The Lancet Neurology, 2006 - thelancet.com
The causes of Parkinson's disease (PD), the second most common neurodegenerative
disorder, are still largely unknown. Current thinking is that major gene mutations cause only …

Time trends in the incidence of Parkinson disease

R Savica, BR Grossardt, JH Bower, JE Ahlskog… - JAMA …, 2016 - jamanetwork.com
Importance Changes over time in the incidence of parkinsonism and Parkinson disease
(PD) remain uncertain. Objective To investigate secular trends (period effects) and birth …

Parkinson's disease

AJ Lees, J Hardy, T Revesz - The Lancet, 2009 - thelancet.com
Parkinson's disease is a common progressive bradykinetic disorder that can be accurately
diagnosed. It is characterised by the presence of severe pars-compacta nigral-cell loss, and …

What genetics tells us about the causes and mechanisms of Parkinson's disease

O Corti, S Lesage, A Brice - Physiological reviews, 2011 - journals.physiology.org
Parkinson's disease (PD) is a common motor disorder of mysterious etiology. It is due to the
progressive degeneration of the dopaminergic neurons of the substantia nigra and is …

Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity

SK Van Den Eeden, CM Tanner… - American journal of …, 2003 - academic.oup.com
The goal of this study was to estimate the incidence of Parkinson's disease by age, gender,
and ethnicity. Newly diagnosed Parkinson's disease cases in 1994–1995 were identified …