[HTML][HTML] Applications of single‑cell omics and spatial transcriptomics technologies in gastric cancer

L Ren, D Huang, H Liu, L Ning… - Oncology …, 2024 - … .spandidos-publications.com
Gastric cancer (GC) is a prominent contributor to global cancer‑related mortalities, and a
deeper understanding of its molecular characteristics and tumor heterogeneity is required …

Enzyme Databases in the Era of Omics and Artificial Intelligence

U Prešern, M Goličnik - International Journal of Molecular Sciences, 2023 - mdpi.com
Enzyme research is important for the development of various scientific fields such as
medicine and biotechnology. Enzyme databases facilitate this research by providing a wide …

Cm-siRPred: Predicting chemically modified siRNA efficiency based on multi-view learning strategy

T Liu, J Huang, D Luo, L Ren, L Ning, J Huang… - International Journal of …, 2024 - Elsevier
The rational modification of siRNA molecules is crucial for ensuring their drug-like
properties. Machine learning-based prediction of chemically modified siRNA (cm-siRNA) …

[HTML][HTML] SAGESDA: Multi-GraphSAGE networks for predicting SnoRNA-disease associations

BM Momanyi, YW Zhou, BK Grace-Mercure… - Current Research in …, 2024 - Elsevier
Over the years, extensive research has highlighted the functional roles of small nucleolar
RNAs in various biological processes associated with the development of complex human …

E-mula: an ensemble multi-localized attention feature extraction network for viral protein subcellular localization

GM Bakanina Kissanga, H Zulfiqar, S Gao, SB Yussif… - Information, 2024 - mdpi.com
Accurate prediction of subcellular localization of viral proteins is crucial for understanding
their functions and developing effective antiviral drugs. However, this task poses a …

The prediction of Recombination Hotspot Based on Automated Machine Learning

DX Ye, JW Yu, R Li, YD Hao, TY Wang, H Yang… - Journal of Molecular …, 2024 - Elsevier
Meiotic recombination plays a pivotal role in genetic evolution. Genetic variation induced by
recombination is a crucial factor in generating biodiversity and a driving force for evolution …

ncRS: A resource of non-coding RNAs in sepsis

B Zhong, Y Dai, L Chen, X Xu, Y Lan, L Deng… - Computers in Biology …, 2024 - Elsevier
Sepsis, a life-threatening condition triggered by the body's response to infection, presents a
significant global healthcare challenge characterized by disarrayed host responses …

[HTML][HTML] Research on Bitter Peptides in the Field of Bioinformatics: A Comprehensive Review

S Liu, T Shi, J Yu, R Li, H Lin, K Deng - International Journal of Molecular …, 2024 - mdpi.com
Bitter peptides are small molecular peptides produced by the hydrolysis of proteins under
acidic, alkaline, or enzymatic conditions. These peptides can enhance food flavor and offer …

Prediction of miRNAs and diseases association based on sparse autoencoder and MLP

SL Sun, BW Zhou, SZ Liu, YH Xiu, A Bilal… - Frontiers in …, 2024 - frontiersin.org
Introduction: MicroRNAs (miRNAs) are small and non-coding RNA molecules which have
multiple important regulatory roles within cells. With the deepening research on miRNAs …

[HTML][HTML] Investigation of in silico studies for cytochrome P450 isoforms specificity

Y Wei, L Palazzolo, OB Mariem, D Bianchi… - Computational and …, 2024 - Elsevier
Abstract Cytochrome P450 (CYP450) enzymes comprise a highly diverse superfamily of
heme-thiolate proteins that responsible for catalyzing over 90% of enzymatic reactions …