Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials

AS Antonopoulos, M Margaritis, R Lee… - Current …, 2012 - ingentaconnect.com
Ample evidence exists in support of the potent anti-inflammatory properties of statins. In cell
studies and animal models statins exert beneficial cardiovascular effects. By inhibiting …

Management of statin intolerance in 2018: still more questions than answers

PP Toth, AM Patti, RV Giglio, D Nikolic… - American Journal of …, 2018 - Springer
Statin therapy is generally well tolerated and very effective in the prevention and treatment of
cardiovascular disease, regardless of cholesterol levels; however, it can be associated with …

Effect of colchicine on myocardial injury in acute myocardial infarction

N Mewton, F Roubille, D Bresson, C Prieur, C Bouleti… - Circulation, 2021 - Am Heart Assoc
Background: Inflammation is a key factor of myocardial damage in reperfused ST-segment–
elevation myocardial infarction. We hypothesized that colchicine, a potent anti-inflammatory …

V Diretriz da Sociedade Brasileira de Cardiologia sobre tratamento do infarto agudo do miocárdio com supradesnível do segmento ST

LS Piegas, A Timerman, GS Feitosa… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Step‐by‐step diagnosis and management of the nocebo/drucebo effect in statin‐associated muscle symptoms patients: a position paper from the International Lipid …

PE Penson, E Bruckert, D Marais… - Journal of cachexia …, 2022 - Wiley Online Library
Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with
statin therapy [most commonly statin‐associated muscle symptoms (SAMS)] result in the …

Pleiotropic effects of statins: new therapeutic targets in drug design

O Bedi, V Dhawan, PL Sharma, P Kumar - … -Schmiedeberg's archives of …, 2016 - Springer
The HMG Co-enzyme inhibitors and new lipid-modifying agents expand their new
therapeutic target options in the field of medical profession. Statins have been described as …

Treating influenza with statins and other immunomodulatory agents

DS Fedson - Antiviral Research, 2013 - Elsevier
Statins not only reduce levels of LDL-cholesterol, they counteract the inflammatory changes
associated with acute coronary syndrome and improve survival. Similarly, in patients …

Statins and delirium during critical illness: a multicenter, prospective cohort study

A Morandi, CG Hughes, JL Thompson… - Critical care …, 2014 - journals.lww.com
Objective: Since statins have pleiotropic effects on inflammation and coagulation that may
interrupt delirium pathogenesis, we tested the hypotheses that statin exposure is associated …

Comprehensive efforts to increase adherence to statin therapy

A Vonbank, S Agewall, KP Kjeldsen… - European heart …, 2017 - academic.oup.com
Previous work from the European Society of Cardiology (ESC), the European
Atherosclerosis Society (EAS) and from other groups has addressed the benefits of statin …

[HTML][HTML] Effects of cardiovascular risk factor variability on health outcomes

SH Lee, MK Kim, EJ Rhee - Endocrinology and Metabolism, 2020 - synapse.koreamed.org
Innumerable studies have suggested “the lower, the better” for cardiovascular risk factors,
such as body weight, lipid profile, blood pressure, and blood glucose, in terms of health …