Citrus flavonoids and their antioxidant evaluation

Y Wang, XJ Liu, JB Chen, JP Cao, X Li… - Critical Reviews in …, 2022 - Taylor & Francis
The antioxidant ability is the link and bridge connecting a variety of biological activities.
Citrus flavonoids play an essential role in regulating oxidative stress and are an important …

On the neuroprotective effects of naringenin: pharmacological targets, signaling pathways, molecular mechanisms, and clinical perspective

Z Nouri, S Fakhri, FF El-Senduny, N Sanadgol… - Biomolecules, 2019 - mdpi.com
As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …

Cellular and molecular mechanisms mediating methylmercury neurotoxicity and neuroinflammation

JP Novo, B Martins, RS Raposo, FC Pereira… - International journal of …, 2021 - mdpi.com
Methylmercury (MeHg) toxicity is a major environmental concern. In the aquatic reservoir,
MeHg bioaccumulates along the food chain until it is consumed by riverine populations …

[HTML][HTML] Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases

HS Arruda, IA Neri-Numa, LA Kido, MRM Júnior… - Journal of Functional …, 2020 - Elsevier
Ageing is an emerging global public health concern due to the increasing number of elderly
people and ageing-related degenerative disorders. Given the absence of effective …

Naringenin: its chemistry and roles in neuroprotection

AV Atoki, PM Aja, TS Shinkafi, EN Ondari… - Nutritional …, 2024 - Taylor & Francis
According to epidemiological research, as the population ages, neurological illnesses are
becoming a bigger issue. Despite improvements in the treatment of these diseases, there …

Citrus polyphenols in brain health and disease: current perspectives

MG Pontifex, MMAH Malik, E Connell… - Frontiers in …, 2021 - frontiersin.org
In addition to essential micronutrients such as vitamin C, citrus fruits represent a
considerably rich source of non-essential bioactive compounds, in particular flavanones …

A review on the protective effects of naringenin against natural and chemical toxic agents

K Naraki, R Rezaee, G Karimi - Phytotherapy Research, 2021 - Wiley Online Library
Naringenin (NRG), as a flavanone from flavonoids family, is widely found in grapefruit,
lemon tomato, and Citrus fruits. NRG has shown strong anti‐inflammatory and antioxidant …

Naringenin alleviates 6-hydroxydopamine induced Parkinsonism in SHSY5Y cells and zebrafish model

S Kesh, RR Kannan, A Balakrishnan - … and Physiology Part C: Toxicology & …, 2021 - Elsevier
Hydroxydopamine (6-OHDA) is a neurotoxin that inhibits the mitochondrial complex I
causing mitochondrial impairment, aetiology of Parkinson's. Naringenin is a flavanone …

Cognitive and biological effects of citrus phytochemicals in subjective cognitive decline: a 36-week, randomized, placebo-controlled trial

S Galluzzi, R Zanardini, C Ferrari, S Gipponi… - Nutrition Journal, 2022 - Springer
Background Auraptene (AUR) and naringenin (NAR) are citrus-derived phytochemicals that
influence several biological mechanisms associated with cognitive decline, including …

Naringenin alleviates cognition deficits in high‐fat diet‐fed SAMP8 mice

T Zhou, L Liu, Q Wang, Y Gao - Journal of Food Biochemistry, 2020 - Wiley Online Library
Naringenin is a natural dihydro flavonoid that is abundant in grapefruit. Previous studies
suggested the cognition protective effect of naringenin in various cognitive deficits models …