[HTML][HTML] Role of exosomes in dermal wound healing: a systematic review

A Prasai, JW Jay, D Jupiter, SE Wolf… - Journal of Investigative …, 2022 - Elsevier
Cell-based therapy imparts its therapeutic effects through soluble GFs and vesicular bodies
such as exosomes. A systematic review with a meta-analysis of preclinical studies was …

Influence of pain and analgesia on orthopedic and wound-healing models in rats and mice

MK Huss, SA Felt, C Pacharinsak - Comparative Medicine, 2019 - ingentaconnect.com
The surgical stress response and resulting physiologic changes can lead to postoperative
complications and negatively impact animal welfare. Although appropriate pain …

Double membrane based on lidocaine-coated polymyxin-alginate nanoparticles for wound healing: In vitro characterization and in vivo tissue repair

DML Oliveira, PS Rezende, TC Barbosa… - International Journal of …, 2020 - Elsevier
The aim of this study was to develop and characterize a double layer biomembrane for dual
drug delivery to be used for the treatment of wounds. The membrane was composed of …

Lidocaine-loaded solid lipid microparticles (SLMPs) produced from gas-saturated solutions for wound applications

C López-Iglesias, C Quílez, J Barros, D Velasco… - Pharmaceutics, 2020 - mdpi.com
The delivery of bioactive agents using active wound dressings for the management of pain
and infections offers improved performances in the treatment of wound complications. In this …

Depletion of langerin+ cells enhances cutaneous wound healing

A Rajesh, G Stuart, N Real, J Ahn, A Tschirley… - …, 2020 - Wiley Online Library
Langerin is a C‐type lectin receptor that is expressed on Langerhans cells and langerin‐
positive dermal dendritic cells in the skin. Little is known about the function of langerin+ cells …

Recent advancements on the synthesis and biological significance of pipecolic acid and its derivatives

MM Al-Rooqi, EU Mughal, QA Raja, RJ Obaid… - Journal of Molecular …, 2022 - Elsevier
Pipecolic acids are cyclic non-protein amino acids serving as precursors for the biosynthesis
of biological metabolites. Structurally, the six-membered cyclic motif consists of five-carbons …

The Wound Reporting in Animal and Human Preclinical Studies Guidelines

N Ojeh, NM Vecin, I Pastar, SW Volk… - Wound Repair and …, 2025 - Wiley Online Library
Preclinical studies for wound healing disorders are an essential step in translating
discoveries into therapies. Also, they are an integral component of initial safety screening …

Local anesthetics infiltration and wound healing process

J Abrão, M Antunes… - Topics in Local …, 2020 - books.google.com
It is a good practice, nowadays, to infiltrate local anesthetics along the incision to prevent
postoperative pain. This can reduce the use of opioids and the side effects they cause. It is …

The Effect of Dexmedetomidine and Levobupivacaine in an Experimental Ischemia Reperfusion Model

TH Ibrahim, K Sevgi, O Sibel, CA Surhan, K Kaan… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Although it has been reported that different molecules are effective in
preventing ischemia-reperfusion (I/R) injury, the most effective treatment is still unknown …

Antinociceptive and wound healing effects of a commercial formulation of lidocaine, bupivacaine, adrenaline and cetrimide applied topically to superficial skin wounds …

S Pratt, A Sole‐Guitart, K de Klerk, E Evans… - Veterinary …, 2024 - Wiley Online Library
Background Post‐traumatic distal limb wounds cause discomfort and heal gradually by
second intention. The topical application of Tri‐Solfen (lidocaine hydrochloride, bupivacaine …