Nanopore-based fourth-generation DNA sequencing technology

Y Feng, Y Zhang, C Ying, D Wang… - Genomics, Proteomics …, 2015 - academic.oup.com
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …

Nutritional metabolomics: progress in addressing complexity in diet and health

DP Jones, Y Park, TR Ziegler - Annual review of nutrition, 2012 - annualreviews.org
Nutritional metabolomics is rapidly maturing to use small-molecule chemical profiling to
support integration of diet and nutrition in complex biosystems research. These …

Perspective—challenges in biomedical analysis: from classical sensors to stochastic sensors

RI Stefan-van Staden - ECS Sensors Plus, 2022 - iopscience.iop.org
Biomedical analysis needs fast reliable screening methods able to identify and also quantify
substances of clinical interest. Diseases such as, cancer, diabetes, corona, influenza, stroke …

Nanopore detection of metal ions: current status and future directions

GM Roozbahani, X Chen, Y Zhang, L Wang… - Small …, 2020 - Wiley Online Library
In this review, recent research efforts that aimed at developing nanopore sensors for
detection of metal ions, which play a crucial role in environmental safety and human health …

Nanofluidic devices with two pores in series for resistive-pulse sensing of single virus capsids

ZD Harms, KB Mogensen, PS Nunes, K Zhou… - Analytical …, 2011 - ACS Publications
We report fabrication and characterization of nanochannel devices with two nanopores in
series for resistive-pulse sensing of hepatitis B virus (HBV) capsids. The nanochannel and …

Slowing DNA translocation through nanopores using a solution containing organic salts

RSS de Zoysa, DA Jayawardhana, Q Zhao… - The Journal of …, 2009 - ACS Publications
One of the key challenges to nanopore DNA sequencing is to slow down DNA translocation.
Here, we report that the translocation velocities of various DNA homo-and copolymers …

Nanopore stochastic detection: diversity, sensitivity, and beyond

G Wang, L Wang, Y Han, S Zhou… - Accounts of chemical …, 2013 - ACS Publications
Nanopore sensors have emerged as a label-free and amplification-free technique for
measuring single molecules. First proposed in the mid-1990s, nanopore detection takes …

Peptide-mediated nanopore detection of uranyl ions in aqueous media

GM Roozbahani, X Chen, Y Zhang, R Xie, R Ma… - ACS …, 2017 - ACS Publications
Uranium is one of the most common radioactive contaminants in the environment. As a
major nuclear material in production, environmental samples (like soil and groundwater) can …

Analysis with biological nanopore: On-pore, off-pore strategies and application in biological fluids

Y Wang, Y Zhang, X Chen, X Guan, L Wang - Talanta, 2021 - Elsevier
Inspired from ion channels in biology, nanopores have been developed as promising
analytical tools. In principle, nanopores provide crucial information from the observation and …

Chemistry solutions to facilitate nanopore detection and analysis

L Wang, H Wang, X Chen, S Zhou, Y Wang… - Biosensors and …, 2022 - Elsevier
Characteristic ionic current modulations will be produced in a single molecule manner
during the communication of individual molecules with a nanopore. Hence, the information …