Ischemia-reperfusion (I/R) injury associated with liver transplantation remains a serious
complication in clinical practice, in spite of several attempts to solve the problem. The …

Results The basic mechanism of hepatic ischemia–reperfusion injury is one of blood
deprivation during ischemia, followed by the return of flow during reperfusion. It involves a …

Background Vascular occlusion is used to reduce blood loss during liver resection surgery.
There is considerable controversy regarding whether vascular occlusion should be used or …

The mitogen-activated protein kinase signaling pathway can be activated by a variety of
growth factors, cytokines, and hormones, and mediates numerous intracellular signals …

Background: Ischemia‐reperfusion (I/R) injury associated with hepatic resections and liver
transplantation remains a serious complication in clinical practice, in spite of several …

Reperfusion injury is the paradoxical and complex phenomenon of exacerbation of cellular
dysfunction and increase in cell death after the restoration of blood flow to previously …

Hypothermic machine preservation (HMP) has been used in renal transplantation since the
late 1960s with recent robust prospective, multicenter data showing lower rates of delayed …

Ischemia and reperfusion (I/Rp) injury is inherent to solid organ transplantation and can
result in primary nonfunction or delayed function of grafts, which is associated with a …

At some point in the natural course of colorectal cancer up to 50% of patients will develop
metastasis to the liver. Historically only 20% of these patients would have to be deemed …

A rat HIRI model was constructed and treated with an intraperitoneal injection of agomir-miR-
494 or agomir-NC (negative control) for 7 days after the surgery. The pathophysiological …