Although low risk localised prostate cancer has an excellent prognosis owing to effective
treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic …

Glioblastoma is a primary malignant brain tumor with a median survival under 2 years. The
poor prognosis glioblastoma caries is largely due to cellular invasion, which enables escape …

Glioblastoma multiforme (GBM) is notoriously resistant to immunotherapy due to its intricate
immunosuppressive tumor microenvironment (TME). Dysregulated cholesterol metabolism …

Gliomas are highly lethal tumours characterised by heterogeneous molecular features,
producing various metabolic phenotypes leading to therapeutic resistance. Lipid metabolism …

Glioblastoma (GBM) is the most lethal malignant tumor in the central nervous system, with a
median survival of only 14 months. Cholesterol, which is the main component of cell …

Epitranscriptomic modifications can affect every aspect of RNA biology, including stability,
transport, splicing, and translation, participate in global intracellular mRNA metabolism, and …

Gliomas are the most common primary malignant brain tumor in adults, but current treatment
for glioblastoma multiforme (GBM) is insufficient. Even though glucose is the primary …

Glioblastoma multiforme (GBM) is an aggressive malignancy of the brain and spinal cord
with a poor life expectancy. The low survivability of GBM patients can be attributed, in part, to …

Our understanding of prostate cancer (PCa) has shifted from solely caused by a few genetic
aberrations to a combination of complex biochemical dysregulations with the prostate …

In recent years, the direct interaction between cancer cells and tumor microenvironment
(TME) has emerged as a crucial regulator of tumor growth and a promising therapeutic …