Hydroalkoxylation-Initiated Cascade on Sulfone-Tethered Aryl Alkynols Gives Cyclic and Spiro-Heterocyclic β-Ketosulfones
Serendipitous formation of cyclic β-ketosulfones is observed when sulfone-tethered
arylalkynols are reacted with base. The reaction involves a base-promoted propargyl …
arylalkynols are reacted with base. The reaction involves a base-promoted propargyl …
New Avenues for the Synthesis of Oxa‐Cycles Using Lewis/Brønsted Acid Mediated Carboxygenation and Carboalkoxylation of Alkynes
The cascade functionalizations of alkynes have provided many elegant methods for the
synthesis of useful scaffolds. Amongst these functionalizations, the ones comprising C− C …
synthesis of useful scaffolds. Amongst these functionalizations, the ones comprising C− C …
Formal [4+2] Cycloaddition of o‐Aza‐Quinone Methide for the Synthesis of 1,4‐Heterocycle‐Fused Quinolines
SJ Gharpure, SK Nanda… - Advanced Synthesis & …, 2021 - Wiley Online Library
A protocol involving intramolecular formal [4+ 2]‐cycloaddition of in situ generated o‐aza‐
quinone methide for the facile synthesis of 1, 4‐heterocycle‐fused quinoline motifs is …
quinone methide for the facile synthesis of 1, 4‐heterocycle‐fused quinoline motifs is …
Regioselective synthesis of spiro quinazolinones via sequential hydroalkoxylation and intramolecular amide-cyclization of alkynol ureas
A TfOH-mediated, metal-free protocol for the synthesis of spiro-furan/pyran quinazolinones
through a cascade hydroalkoxylation and intramolecular amide-cyclization reaction of …
through a cascade hydroalkoxylation and intramolecular amide-cyclization reaction of …
Seven-membered rings
This chapter covers work published in the calendar year 2020. Novel reaction chemistry and
new ring-synthetic methods for seven-membered heterocycles including azepines …
new ring-synthetic methods for seven-membered heterocycles including azepines …