Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

Senescence and impaired DNA damage responses in alpha-synucleinopathy models

YS Yoon, JS You, TK Kim, WJ Ahn, MJ Kim… - … & Molecular Medicine, 2022 - nature.com
Abstract α-Synuclein is a crucial element in the pathogenesis of Parkinson's disease (PD)
and related neurological diseases. Although numerous studies have presented potential …

Cancer progression gene expression profiling identifies the urokinase plasminogen activator receptor as a biomarker of metastasis in cutaneous squamous cell …

E Minaei, SA Mueller, B Ashford, AS Thind… - Frontiers in …, 2022 - frontiersin.org
Cutaneous squamous cell carcinoma (cSCC) of the head and neck region is the second
most prevalent skin cancer, with metastases to regional lymph nodes occurring in 2%–5% of …

RedRibbon: A new rank–rank hypergeometric overlap for gene and transcript expression signatures

A Piron, F Szymczak, T Papadopoulou… - Life science …, 2024 - life-science-alliance.org
High-throughput omics technologies have generated a wealth of large protein, gene, and
transcript datasets that have exacerbated the need for new methods to analyse and …

miRNA expression signatures of therapy response in squamous cell carcinomas

JT Fekete, Á Welker, B Győrffy - Cancers, 2020 - mdpi.com
Simple Summary miRNAs play role in various diseases and can also modulate therapy
response. Our aim was to identify predictive miRNAs in platinum treated squamous cell …

GeneCompete: an integrative tool of a novel union algorithm with various ranking techniques for multiple gene expression data

P Janyasupab, A Suratanee, K Plaimas - PeerJ Computer Science, 2023 - peerj.com
Background Identifying the genes responsible for diseases requires precise prioritization of
significant genes. Gene expression analysis enables differentiation between gene …

[HTML][HTML] Efficient and precise cell counting for RNAi screening of Orientia tsutsugamushi infection using deep learning techniques

P Kanchanapiboon, C Songsaksuppachok… - Intelligent Systems with …, 2024 - Elsevier
Acquiring fluorescent scrub typhus images obtained through RNA interference screening for
the analysis of 60 different human genes and 18 control genes poses challenges due to …

RedRibbon: A new rank-rank hypergeometric overlap pipeline to compare gene and transcript expression signatures

A Piron, F Szymczak, MI Alvelos, M Defrance… - BioRxiv, 2022 - biorxiv.org
Motivation High throughput omics technologies have generated a wealth of large protein,
gene and transcript datasets that have exacerbated the need for new methods to analyse …

Capture-recapture for-omics data meta-analysis

J Juodakis - bioRxiv, 2023 - biorxiv.org
One of the major goals of modern-omics studies, in particular genome-wide association
studies (GWASs), is to understand the polygenicity of various traits, ie the number of genetic …

[PDF][PDF] Prediktív biomarkerek vizsgálata különböző daganattípusokban

JT Fekete - 2022 - repo.lib.semmelweis.hu
Az emlőtumorok esetében például az ösztrogén, a progeszteron, illetve a HER2 receptorok
kifejeződése nem csak prognosztikus, de prediktív, a gyógyszeres terápiát meghatározó …