Gas6 (growth arrest-specific gene 6) is a widely expressed vitamin K-dependent protein that
is involved in many biological processes such as homeostatic regulation, inflammation and …

Renal fibrosis is the most common pathological manifestation of a wide variety of chronic
kidney disease. Increased extracellular matrix (ECM) secretion and enhanced …

Objective. Mitochondrial damage contributes to extracellular matrix (ECM) deposition and
renal fibrosis. In this study, we aimed (1) to investigate whether fluorofenidone (AKF‐PD) …

The leading cause of atherosclerotic cardiovascular disease (ASCVD) is elevated low-
density lipoprotein cholesterol (LDL-C). Proprotein convertase subtilisin/kexin type 9 …

C-Amino-1, 2, 4-triazoles are challenging polynitrogen substrates for metal-catalyzed
arylation due to their multidentate character, enhanced coordinating ability and decreased …

Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disease, demands
effective medication to alleviate symptoms. This study focused on sleep impairment as an …

In addition to the classical resistance mechanisms, receptor tyrosine-protein kinase AXL is a
main mechanism of resistance to third-generation epidermal growth factor receptor-tyrosine …

Innate immune cells are important in the initiation and potentiation of alloimmunity in
transplantation. Immediately upon organ anastomosis and reperfusion, recipient monocytes …

At present, TGF-β is the most critical fibrogenic factor known. Smad ubiquitin ligase Smurfs
play an important role in the regulation of the TGF-/Smads signaling pathway, which is …

Mitochondrial homeostasis plays essential role for the proper functioning of the kidney.
NADH‐ubiquinone oxidoreductase core subunit V1 (NDUFV1) is an enzyme in the complex …